Objective and Study Design: The present study has been undertaken to evaluate the protective efficacy of lycopene on cadmium induced toxicity in heart of albino mice. Materials and Methods: 24 Albino mice were divided into four groups. Group I mice were kept as control. Group II animals were administered a single dose of cadmium chloride (0.32mg/kg bw) intraperitoneally. Group III animals were ...

Objective: Evaluation of anti cancer activity of methanol extracts of Curcuma zedoaria against Ehrlich’s ascities carcinoma (EAC) cell line in Swiss albino mice. Method: In vitro cytotoxicity assay has been evaluated by using the trypan blue and MTT assay method. In vivo anti cancer activity was performed by using EAC cells induced mice groups (n=12), at the doses of 100 and 200 mg/kg b.w. resp...

Abstract: Purpose: The present work evaluated the neuroprotective potential of embelin either alone and in combination with Levodopa rotenone induced PD (Parkinson’s disease) model mice. Methods: Swiss albino male adult mice were randomly divided into 7 groups. Group-1 (Control) received 2mL/kg olive oil by oral route (p.o.), Groups from 2 to 2.5mg/kg intraperitoneal (i.p.), levodopa was admini...

Triple antimalarial combination therapies may overcome the emergence of drug resistance. Sulfadoxine/pyrimethamine (S/P) is an drug. Clindamycin (C) has potential antiplasmodial effect. This study assessed whether activity S/P can be augmented by C on Plasmodium berghei-infected mice. Adult Swiss albino mice (25-30g) were grouped and infected with berghei. The orally treated daily (21.4/10.7 mg...

The length of oestrous cycles in a group of mature albino mice has been measured by the technique of daily vaginal smears. A high proportion of mice had prolonged cycles. It was shown that mice housed singly may experience abnormal cycles, the number being least when a wire loop is used for taking the smears. Housing mice in groups of four brought about an immediate cessation of normal cycling ...