Albino animals display a hypopigmented phenotype associated with several visual abnormalities, including rod photoreceptor cell deficits, abnormal patterns of connections between the eye and the brain and a general underdevelopment of central retina. Oculocutaneous albinism type I, a common form of albinism, is caused by mutations in the tyrosinase gene. In mice, the albino phenotype can be cor...

INTRODUCTION ................................................................. 325 Established cases of linkage in mice and rats.. ................................ 326 Previous investigations ............................................... 326 Present kvestigation ......................................................... 328 Linkage of pink-eye and albinism in mice.. ..............................

Objective. The aim of this paper is to report the case of a patient diagnosed with Hermansky-Pudlak syndrome, as a result of bleeding diathesis. Clinical Presentation and Intervention. A 23-year-old male presented with recurrent epistaxis and, upon physical examination, was found to be remarkable for albinism and suborbital ecchymosis. The absence of dense bodies in the platelets was demonstrat...

The effects of c and rd on jump-out and one-way avoidance learning were examined using both inbred strains and test crosses. Neither gene was found to retard either escape or avoidance performance in the jump-out task, although rd led to less accurate jumping. One-way performance, which required running through a small hole in a wall, was greatly disrupted in mice homozygous for rd; both escape...

BACKGROUND Basal cell carcinoma is one of the more common cancers worldwide; 2.8 million are diagnosed annually in the USA.  However, the rate at which it metastasizes is considered very low, between 0.0028 and 0.5%.  For those rare cases in which metastases occur, approximately one third metastasize to the lung.  CASE Presented is a 62-year-old Caucasian male with oculocutaneous albinism and...