The article is devoted to the history of coming power and analysis domestic foreign policy President Arab Republic Egypt (ARE), Field Marshal Abd-аl Fattah al-Sisi. author notes that new leader country chose a tough internal political course aimed at strengthening his own suppressing opposition, fi rst all, Muslim Brotherhood (the organization’s activities are prohibited on territory Russian Fe...

Plectin is a major component of the cytoskeleton and links the intermediate filament system to hemidesmosomes by binding to the integrin beta4 subunit. Previously, a binding site for beta4 was mapped on the actin-binding domain (ABD) of plectin and binding of beta4 and F-actin to plectin was shown to be mutually exclusive. Here we show that only the ABDs of plectin and dystonin bind to beta4, w...

Assurance Based Development (ABD) is a novel approach to the synergistic construction of critical software systems and their assurance arguments. In ABD, the need for assurance drives a unique process synthesis mechanism that results in a detailed operational process for building both software and an argument demonstrating its fitness for use in given operating contexts. In this paper, we intro...

W model a situation in which two retailers consider launching an “Advance Booking Discount” (ABD) program. In this program, customers are enticed to precommit their orders at a discount price prior to the regular selling season. However, these precommitted orders are filled during the selling season. While the ABD program enables the retailers to lock in a portion of the customer demand and use...

abu al-al?’ al-ma’arri has presented his specific thought and viewpoint in arabic classical literature. he lived at the time when arabic literature was at its zenith of richness and maturity. this literary and thinking figure has affected the literary men after him in differing ways. contemporary poets, relying on his literature, have promoted their own literary innovations, and thereby have en...

The Drosophila larval cardiac tube is composed of 104 cardiomyocytes that exhibit genetic and functional diversity. The tube is divided into the aorta and the heart proper that encompass the anterior and posterior parts of the tube, respectively. Differentiation into aorta and heart cardiomyocytes takes place during embryogenesis. We have observed living embryos to correlate morphological chang...

the ḥadīth, “backbiting is more severe than adultery” (al-ghaybatu ashaddu min al-zinā), quoted from the apostle of allah (s.a.w.), by four of his companions: abū dhar al-ghifārī, abū sa‘īd al-khudrī, jābir b. ‘abd allāh al-anṣārī, and anas b. al-mālik is reported in the shī‘ī and sunnī sources – except for the kutub al-‘arba‘a and ṣiḥāḥ al-sitta. while analyzing and explaining the text of the ...

Many important processes in eukaryotic cells involve changes in the quantity, location and the organization of actin filaments [1] [2] [3]. We have been able to visualize these changes in live cells using a fusion protein (GFP-ABD) comprising the green fluorescent protein (GFP) of Aequorea victoria and the 25 kDa highly conserved actin-binding domain (ABD) from the amino terminus of the actin c...