s and Poster PresentationsRisacher SL, Yoder KK, West JD, WuDunn D, MaGee TR, McDonald BC,Hutchins GD, Zheng QH, Saykin AJ. Relationship of visual contrast sensitivity toamyloid deposition assessed by [11C] PiB PET. Accepted for poster presentation at the Human Amyloid Imaging Conference, January 12-13, 2012. Wang H, Nie F, Huang H, Risacher SL, Ding C, Saykin AJ, Shen L, and the<lb...

The Deligne-Simpson problem (DSP) (resp. the weak DSP) is formulated like this: give necessary and sufficient conditions for the choice of the conjugacy classes Cj ⊂ GL(n,C) or cj ⊂ gl(n,C) so that there exist irreducible (resp. with trivial centralizer) (p + 1)-tuples of matrices Mj ∈ Cj or Aj ∈ cj satisfying the equality M1 . . .Mp+1 = I or A1+ . . .+Ap+1 = 0. The matrices Mj and Aj are inter...

The problem of existence and uniqueness of polynomial solutions of the Lamé differential equation A(x)y′′ + 2B(x)y′ + C(x)y = 0, where A(x), B(x) and C(x) are polynomials of degree p + 1, p and p − 1, is under discussion. We concentrate on the case when A(x) has only real zeros aj and, in contrast to a classical result of Heine and Stieltjes which concerns the case of positive coefficients rj i...

Compartmentalization of the plasma membrane in a cell is fundamental for its proper functions. In this study, we present evidence that mammalian Fat4 and Dachsous1 cadherins regulate the apical plasma membrane organization in the embryonic cerebral cortex. In neural progenitor cells of the cortex, Fat4 and Dachsous1 were concentrated together in a cell-cell contact area positioned more apically...

Abstrakt: V príspevku sú zhrnuté priebežné výsledky aplikovaného výskumu v oblasti spracovania prirodzeného jazyka v úlohách orientovaných na výskum a vývoj modulov rečových rozhraní medzi človekom a strojom, ktorý prebieha v Laboratóriu rečových a mobilných technológií na KEMT FEI TU v Košiciach. Zahrnutie hovorenej reči, ako najprirodzenejšieho komunikačného nástroja medzi l’ud’mi, má svoje n...

Clusters of galaxies are important laboratories for understanding both galaxy evolution and constraining cosmological quantities. Any analysis of clusters, however, is best done when one can reliably determine which galaxies are members of the cluster. While this would ideally be done spectroscopically, the difficulty in acquiring a complete sample of spectroscopic redshifts becomes rather daun...

The LRRK2 G2019S mutation is found at higher frequency among Parkinson disease (PD) patients of Ashkenazi Jewish (AJ) ancestry. This study was designed to test whether an internet-based approach could be an effective approach to screen and identify mutation carriers. Individuals with and without PD of AJ ancestry were recruited and consented through an internet-based study website. An algorithm...

The adherens junction (AJ) and tight junction (TJ) are key regulators of epithelial polarity and barrier function. Loss of epithelial phenotype is accompanied by endocytosis of AJs and TJs via unknown mechanisms. Using a model of calcium depletion, we defined the pathway of internalization of AJ and TJ proteins (E-cadherin, p120 and beta-catenins, occludin, JAM-1, claudins 1 and 4, and ZO-1) in...