It is generally believed that base-pair stacking interaction in DNA double helix is one of the strongest interactions that governs sequence directed structural variability. However, X-ray crystal structures of some base-paired doublet sequences have been seen to adopt different structures when flanked by different base-pairs. DNA crystal database, however, is still too small to make good statis...

Despite of over a century of scientific effort, the understanding in earthquake forecasting remains immature. Moreover, even the theoretical possibility of earthquake forecasting is debatable. Especially problematic is a possibility of an effective shortand intermediate-term earthquake forecasting. The aim of this paper is to present the new evidence in support of possibility of the shortand in...

— An Earthquake is more important for geophysics and economy problems. The Support Vector Machine of data mining techniques with cluster analysis is used to predict impact of earthquake [2]. The historical data are collected which has follow the time series methodology, combine the data mining for pre-processing and finally apply the SVM to predict the impact of earthquake. Earthquake predictio...

This paper presents a review of the work done in earthquake prediction using abnormal animal behavior. The earthquake prediction can be done using the abnormal behavior of animals preceding earthquake occurrence in seismically active region because of their relatively more capability than humans of perceiving certain kind of geophysical stimuli which may precede earthquake. The international wo...

The Collaboratory for the Study of Earthquake Predictability (CSEP) aims to advance earthquake research by rigorous testing of earthquake forecast hypotheses. As in other disciplines, such hypothesis testing requires carefully designed experiments that meet certain requirements: they should be reproducible, fully transparent, and conducted within a controlled environment. CSEP has begun buildin...

Severe soil liquefaction due to a long duration earthquake with low acceleration occurred at Tokyo Bay area in the 2011 off the Pacific coast of Tohoku Earthquake. This phenomenon clearly shows that soil liquefaction is affected by properties of input waves. This paper describes effect of wave properties of earthquake on liquefaction using effective stress analysis with some earthquakes. Analyt...

INTRODUCTION In recent years, several massive earthquakes have occurred across the globe. Multidetector computed tomography (MDCT) is reliable in detecting spinal injuries. The purpose of this study was to compare the features of spinal injuries resulting from the Sichuan earthquake with those of non-earthquake-related spinal trauma using MDCT. METHODS Features of spinal injuries of 223 Sichu...

BACKGROUND For patients with advanced gastric cancer (AGC), second-line chemotherapy regimen remains controversial. The efficacy and safety of irinotecan-containing doublet treatment and irinotecan monotherapy were compared in this systematic analysis. METHODS A search was conducted on EMBASE and Medline databases. All articles compared irinotecan-containing doublet to irinotecan as second-li...

Enzymes in Uracil DNA glycosylase (UDG) superfamily are essential for the removal of uracil. Family 4 UDGa is a robust uracil DNA glycosylase that only acts on double-stranded and single-stranded uracil-containing DNA. Based on mutational, kinetic and modeling analyses, a catalytic mechanism involving leaving group stabilization by H155 in motif 2 and water coordination by N89 in motif 3 is pro...

Discrete time-varying autoregressive moving average (ARMA) models are used to describe realistic earthquake ground motion time histories. Both amplitude and frequency nonstationarities are incorporated in the model. An iterative Kalman filtering scheme is introduced to identify the time-varying parameters of an ARMA model from an actual earthquake record. Several model verification tests are pe...