Introdução: A síndrome inflamatória aguda ocasionada pela COVID-19 amplifica o processo inflamatório crônico provocado obesidade, levando a uma cascata ainda mais grave, exacerbando destruição celular dos diferentes tecidos afetados doença, incluindo os olfativo e gustativo. Objetivos: elucidar resumir correlação entre as alterações oro-naso-sensoriais, COVID-19. Metodologia: Trata-se de revisã...

Background: Since December 2019 the novel coronavirus (SARS-CoV-2) is center of global attention due to its rapid transmission and toll on health care systems economy. Population-based serosurveys measuring antibodies for SARS-CoV-2 provide one method estimating previous infection rates including symptom-free courses disease monitoring progression epidemic. Methods: In June 2020 we succeeded in...

Vírus é um ser vivo que não formado por estrutura celular. Os vírus podem transmitidos contato direto com indivíduos infectados ou de forma indireta superfícies contaminadas. Definido como uma nova variedade coronavírus, a COVID 19 fez Organização Mundial Saúde (OMS) declarar no começo 2020 crise na saúde pública global. Considerando-se alta transmissibilidade deste vírus, foi necessário adotar...

The new coronavirus, called SARS-Cov-2, discovered in December 2019 Wuhan, China, is already responsible for more than 3 million deaths worldwide, according to the WHO. virus attacking respiratory, digestive and nervous systems, invading cells of these systems that have angiotensin-converting enzyme receptor 2 (ACE-2). disease being continuously studied scientific findings are every day. One mo...

Background: Smoking is the cause of inducing changes in taste functionality under conditions of chronic exposure. The objective of this study was to evaluate taste sensitivity in young smokers and non-smokers and identify any differences in the shape, density and vascularisation of the fungiform papillae (fPap) of their tongue. Methods: Sixty-two male subjects who served in the Greek military f...

Brain-derived neurotrophic factor (BDNF) is expressed in gustatory epithelia and is required for gustatory neurons to locate and innervate their correct target during development. When BDNF is overexpressed throughout the lingual epithelium, beginning embryonically, chorda tympani fibers are misdirected and innervate inappropriate targets, leading to a loss of taste buds. The remaining taste bu...

RATIONALE Cronkhite-Canada syndrome (CCS) is a rare disease, the etiology of CCS is currently unknown. Although CCS is widely accepted as a benign disorder, the malignant potential of the polyps in CCS patients is yet controversial. PATIENT CONCERNS A 55-year-old Chinese male was first admitted to Beijing Friendship Hospital with a 3-month history of frequent watery diarrhea (10-15 times/day)...

BACKGROUND A previous single dose placebo-controlled double-blinded trial showed an extremely low (0.4%) intolerance rate of sodium ferric gluconate complex (SFGC) in SFGC-naive haemodialysis patients. No large prospective trials have assessed the safety of SFGC during repeated exposure in the outpatient haemodialysis setting. METHODS Chronic haemodialysis patients completing the single-dose ...

Comparative and evolutionary biology can not only verify laboratory findings of gene functions but also provide insights into their physiological roles in nature that are sometimes difficult to discern in the laboratory. Specifically, if our understanding of the physiological function of a gene is complete and accurate, the gene should be inactivated or pseudogenized in and only in organisms in...

TO THE EDITOR: In their paper on salivary gland damage after high-dose radioiodine ablation therapy, Nakada et al. discuss an interesting and practical issue (1). The authors propose a radiation protection paradigm based on a concept of the dynamics of salivary gland function. The authors claim to have compared 2 radiation protection regimens in similar patients groups: a group that started suc...