many investigators are interested in finding the new cultural systems that can support the in vitro development of pre-implantation embryos better. previous studies suggested that growth factors such as epidermal growth factor (egf) are important in pre-implantation embryo development and implantation process. on the other hand, it is very important to support post thaw development of frozen em...

background: induction of ovulation in art is necessary for superovulation and the side effects of superovulatory drugs are debated. oxytocin as a natural hormone, have receptors and is synthesized by several reproductive organs. preovulatory presence of oxytocin receptor mrnas in granulosa cells indicating a role for oxytocin in follicular development. objective: the aim of the present study wa...

background: cytotoxic therapy can lead to prolonged azoospermia or even sterility. in the present study, we investigated the morphological changes of mouse testes after gamma-radiation. methods: after anaesthetizing of nmri mice, testes and their surrounding tissues were irradiated using a cobalt therapy machine. four experimental groups were irradiated with fractionated doses of: 1.5+8, 1.5+12...

background: all-trans retinol is a biological antioxidantscavenging the ros in the cell culture. objectives: this studywas conducted to investigate the effect of all-trans retinol infertilization and culture medium on mouse embryo's developmentalcompetence. methods: this study was designed into twoexperiments. in the first experiment, in vitro mature oocytes wereco-cultured with sperm in fertil...