Aflatoxins are potent biological toxins that have been shown to exert a range of acute and chronic pathological effects. Multiple mortality events of waterfowl caused by acute aflatoxicosis have been documented in the USA. However, international concern has recently been expressed regarding the potential effects of chronic exposure of wildlife species to low levels of dietary aflatoxin. This st...

Aflatoxins (AF) are mycotoxins derived by Aspergillus flavus and Aspergillus parasiticus and are listed as Group I carcinogens by the International Agency for Research on Cancer (IARC), a body of the World Health Organization. The main aflatoxins are the B1 (AFB1), B2, G1 and G2 together with their metabolites, among which the most important is the aflatoxin B1. AFB1 is the molecule with the hi...

Aflatoxins, metabolites of the fungus Aspergillus flavus, are potent liver toxins and carcinogens in animals, and may also be human carcinogens. Although aflatoxin contamination in corn is uncommon in Kentucky, occasional incidents do occur and can create significant economic losses for individual producers. Of all the known mycotoxins (toxic substances produced by fungi), aflatoxins in corn an...

Aflatoxins are defined as difuranocyclopentanocumarines/ difuranopentanolidocumarines this contains a dihydrofuran or a tetrahydrofuran ring. One of the most important effects of post harvest decays of fruits, vegetables and especially of seed and feed deterioration by fungi is the produce of mycotoxicoses. This is a disease of animals and humans following consumption of feeds and foods invaded...

Aflatoxins are naturally occurring toxins produced by certain fungi: mainly Aspergillus flavus and Aspergillus parasiticus. Several types of aflatoxins (B1, B2, G1, and G2) are produced by these fungi. The B1 form is recognized by the International Agency for Research on Cancer as one of the most naturally occurring toxic and carcinogenic substances found in nature. 1 These aflatoxin-producing ...

The production of aflatoxins B1 and B2 by Aspergillus tamarii (subgenus Circumdati section Flavi) is reported for the first time. The fungus was isolated from soil collected from a tea (Camellia sinensis) field in Miyazaki Prefecture, Japan. Three single-spore cultures, NRRL 25517, NRRL 25518, and NRRL 25519, were derived from subcultures of the original isolate 19 (MZ2). Each of these single-s...

Abstract Mycotoxins are highly toxic fungal metabolites that can pose health threats to humans and animals. Aflatoxins a type of mycotoxin produced mainly by Aspergillus flavus A. parasiticus . A sensitive high performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) method with multiple reaction monitoring (MRM) modes was developed for the determination aflatoxins in blood after...

Resting cells of Aspergillus parasiticus ATCC 15517 were used to prepare highly labeled aflatoxins from labeled acetate. High synthetic activity in growing cells was evidenced only during 40 to 70 hr of incubation. Glucose was required for high incorporation efficiency, whereas the concentration of the labeled acetate determined the specific activity of the product. When labeled acetate was con...

Sensitive and specific methods are needed for measuring human exposure to carcinogens. Synchronous fluorescence spectrophotometry can be used to measure fmol of aflatoxins, their metabolites, and DNA adducts. Computer-assisted analysis of spectra of these agents obtained by synchronous fluorescence spectrophotometry can be displayed as contour maps which are highly specific for each agent. Indi...

Aflatoxins are naturally occurring toxins produced by certain fungi, mainly Aspergillus flavus and Aspergillus parasiticus. Several types of aflatoxins (B1, B2, G1, and G2) are produced by these fungi. The B1 form is recognized by the International Agency for Research on Cancer as one of the most toxic and carcinogenic substances found in nature. 1 These aflatoxin-producing fungi can contaminat...