Awake craniotomy represents an essential option for surgical procedures requiring a patient’s participation in defining the extent of resection. This includes excision of epileptogenic foci, performed in patients with medically refractory epilepsy. Approximately 2 million Americans with a diagnosis of epilepsy are treated with Antiepileptic Drugs (AEDs), of these 20 percent continue to have sei...

Cytochrome P450 (CYP) 2D6 is an important drug-metabolizing enzyme, and its gene is known to be highly polymorphic. Here, we report five novel nonsynonymous single nucleotide polymorphisms (SNPs), and 65 other sequence variations detected from the gene coding for cytochrome P450 (CYP) 2D6 in 254 Japanese subjects. Two of the novel nonsynonymous SNPs were associated with the *10 key SNP, C100T. ...

Escherichia coli 4 5 Running title: Alanine synthesis in E. coli 6 7 Sok Ho Kim †, Barbara L. Schneider, and Larry Reitzer * 8 9 Department of Molecular and Cell Biology, The University of Texas at Dallas, Richardson, 10 Texas 75080 11 12 † Present address: Department of Biochemistry, UT Southwestern Medical Center, Dallas, Texas 13 14 * Corresponding author. Mailing address: 800 W. Campbell Rd...

We study nonlinear equations subject to oscillatory initial data. The oscillatory solution of such problems tends to a homogenized weak limit that is characterized by the corresponding homogenized equations. Those equations usually involve an additional independent variable, so that the weak limit is an average of infinitely many functions. In certain cases, however, there is an alternative des...

Given the importance and prevalence of commercialization in intercollegiate sport, outsourcing sport marketing functions has become a popular business decision with the possibility of becoming more popular in the future. Yet, there is a lack of research about outsourcing in sport marketing with respect to decision making factors when determining whether or not to outsource some aspects of an or...

In this work, an analysis method is developed for the robust and efficient estimation of 3-D seismic local structural entropy, which is a measure of local discontinuity. This method avoids the computation of large covariance matrices and eigenvalues, associated with the eigenstructure-based and semblance-based coherency estimates. We introduce a number of local discontinuity measures, based on ...

The effect of a common habit among Yemeni population on the periodontal status was investigated. This cross-sectional study was done on 2500 Yemenis with mean age 27.01 years (1818 males and 682 females). Among these 1528 were qat chewers and 972 were non-chewers. Detailed questionnaire and pre-designed scoring system for the periodontal status were employed for each case. Study results indicat...

Pulmonary Arterial Hypertension (PAH) is a disorder defined by elevated mean pulmonary arterial pressure. PAH can be idiopathic or associated with a variety of medical conditions such as scleroderma, congenital heart disease, left heart failure, lung disease or chronic pulmonary thromboembolism. This progressive disease can cause severe right heart failure and death. Normal physiologic changes ...

BACKGROUND Aortic stenosis (AS) leads to diffuse fibrosis in the myocardium, which is linked to adverse outcome. Myocardial T1 values change with tissue composition. OBJECTIVE To test the hypothesis that our recently developed non-contrast cardiac magnetic resonance (CMR) T1 mapping sequence could identify myocardial fibrosis without contrast agent. DESIGN, SETTING AND PATIENTS A prospectiv...

PURPOSE To examine the thickness of the macular choroid and its associations in school children aged 6 to 18 years. METHODS The school-based cross-sectional Shandong Children Eye Study included 6026 (94.7%) of 6364 eligible children fulfilling the inclusion criterion of an age from 4 to 18 years. Spectral-domain optical coherence tomography (SD-OCT) was performed for a subgroup of 972 school ...