Results We included 24 pts [(21M,3F;10.6(4-16)yrs)]; median age at EoEd: 7(1-14)yrs. Average between symptom onset and EoEd:19±30 months. Average follow-up for 28 (5-60) months. Most frequent symptoms (%): dysphagia (54), impaction (50), GERD-like symptoms (42), abdominal and/or epigastric pain (42), vomiting (33). Most frequent onset symptom: dysphagia (46%). 96% of pts had prior history of at...

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by intense polyclonal production of autoantibodies and circulating immune complexes. Some reports have associated SLE with a Th2 immune response and allergy. In the present study 21 female patients with SLE were investigated for total IgE and IgE antibodies to dust house aeroallergens by an automated enzyme-linked fluores...

BACKGROUND The association between sensitizations and severity of allergic diseases is controversial. OBJECTIVE This study was to investigate the association between severity of asthma and rhinitis and degree of specific allergic sensitization in allergic patients in China. METHOD A cross-sectional survey was performed in 6304 patients with asthma and/or rhinitis from 4 regions of China. Pa...

The rising frequency of obstructive respiratory diseases,in particular allergic asthma, observed over the last years, can be partially explained by changes occurring in the environment, with increasing presence in atmosphere of chemical (particulate matter and gaseous components such as nitrogen dioxide and ozone) and biologic (aeroallergens) trigger factors. Aeroallergens are able to stimulate...

BACKGROUND Increased intestinal permeability has been reported in one study of adult asthmatics. AIM To determine whether children with asthma have altered intestinal permeability. METHODS Thirty two asthmatic children, and 32 sex and age matched controls were recruited. The dual sugar (lactulose and mannitol) test was used to evaluate intestinal permeability, and the percentage of ingested...

BACKGROUND Prevalence of respiratory allergic diseases has increased worldwide. Identification of the aeroallergens involved in allergenic sensitisation is important for diagnosis, treatment and prevention. OBJECTIVE To verify the molecular pattern of sensitisation to aeroallergens in patients with allergic respiratory diseases using microarray technique for specific IgE antibody detection. ...