OBJECTIVES To determine the feasibility of the use of a topical vasoconstrictor for hemostasis during functional endoscopic sinus surgery. STUDY DESIGN Case-control study. SUBJECTS AND METHODS From May 1998 to August 2002, 226 patients (injection group) with bilateral chronic rhinosinusitis received an adrenaline injection for hemostasis during functional endoscopic sinus surgery at our ter...

To investigate the influence of neuropeptide Y (NPY) on heart function in a relatively simple model system, the effects of eel NPY (eNPY) on the eel atrium were examined. Eel NPY enhanced the contractile force of the isolated atrium in a dose-dependent manner, without altering the rate of contraction. Although adrenaline also exerts a positive inotropic effect, the effect of eNPY was not blocke...

background: postoperative periorbital edema and ecchymosis are common after rhinoplasty. we studied the effect of local injection of lidocaine/adrenaline immediately before osteotomy on prevention of post-operative periorbital edema and ecchymosis in rhinoplasty. m aterials and methods: thirty healthy candidates for rhinoplasty were enrolled in the self-controlled clinical trial study. lidocain...

Mitochondria isolated from rat hearts perfused with adrenaline, and from hearts excised from adrenaline-treated rats, showed an enhanced rate of respiration-dependent Ca2+ uptake. Adrenaline pretreatment did not change the activity of the Na+/Ca2+-antiporter of isolated heart mitochondria. Simultaneous measurements of the membrane potential revealed that perfusion with adrenaline has no signifi...

The effect of adrenaline on plasminogen activator release was studied in vitro in human vein biopsy specimens, in which the fibrinolytic activity was determined according to the fibrin slide technique. The tissue slides were covered with a thin fibrin film containing 10(-9) and 10(-7) M adrenaline and exposed for 30 to 60 minutes. In both concentrations highly significant (p less than 0.001) en...

A prospective randomized controlled study was carried out in 41 adult neurosurgical patients to find out the hemodynamic effects following scalp infiltration with 0.5% lignocaine with or without adrenaline. The patients were divided randomly into two groups. Group I patients (n=21) received 0.5% lignocaine with adrenaline (1:8,00,000) for scalp infiltration and group II patients (n=20) received...

The present work was carried out as part of a programme ofresearch on the inactivation of L-adrenalne (I) in the body. There are two views ofthe mode ofinactivation ofadrenaline: briefly, the first is that the inactivation inv'olves monoamine oxidase which oxidatively deaminates adrenaline, and the second is that the inactivation takes place through conjugation of the hydroxyl groups of adrenal...