نتایج جستجو برای: adjacent segment degeneration
تعداد نتایج: 218412 فیلتر نتایج به سال:
PURPOSE OF THE STUDY Decompression surgery with or without fusion is the gold standard treatment of lumbar spinal stenosis, but adjacent segment degeneration has been reported as a long-term complication after fusion. This led to the development of dynamic implants like the interspinous devices. They are supposed to limit extension and expand the spinal canal at the symptomatic level, but with ...
Proximal junctional disease is a well-recognized postoperative phenomenon in adults who are undergoing long thoracolumbar fusion and instrumentation, and is attributed to increased a junctional stress concentration. In general, the onset of symptoms in these patients is insidious and the disease progresses slowly. We report on a contrary case of rapidly progressing paraplegia secondary to acute...
OBJECTIVE The objective of this study was to establish a large animal model that recapitulates the spectrum of intervertebral disc degeneration that occurs in humans and which is suitable for pre-clinical evaluation of a wide range of experimental therapeutics. DESIGN Degeneration was induced in the lumbar intervertebral discs of large frame goats by either intradiscal injection of chondroiti...
STUDY DESIGN A prospective cohort study. OBJECTIVE To determine the cause-effect relationship between fusion and sacroiliac joint (SIJ) degeneration after instrumented posterolateral lumbar or lumbosacral fusion. SUMMARY OF BACKGROUND DATA Adjacent segment degeneration following spinal fusion has attracted considerable attention. However, little attention has been paid to the SIJ, which is ...
Mutations in the RP1 gene can cause retinitis pigmentosa. We identified a spontaneous L66P mutation caused by two adjacent point mutations in the Rp1 gene in a colony of C57BL/6J mice. Mice homozygous for the L66P mutation exhibited slow, progressive photoreceptor degeneration throughout their lifespan. Optical coherence tomography imaging found abnormal photoreceptor reflectivity at 1 month of...
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