BACKGROUND An inverse association between serum adiponectin level and metabolic syndrome was seen in few studies. The aim of this study was to assess the association between serum adiponectin levels and metabolic syndrome in a sample of Iranian women from Kerman. METHODS In a cross-sectional study 946 subjects were studied to determine the prevalence of metabolic syndrome and in a case contro...

Leptin and adiponectin are two important adipose tissue derived cytokines. Serum adiponectin levels decrease in obesity and chronic disease, whereas leptin shows a positive correlation with inflammation. Given that serum leptin and adiponectin levels vary among different ethnic groups, the aim of this study was to determine the serum levels of leptin and adiponectin in a random sample of appare...

Plasma Adiponectin Concentrations in Women With Preeclampsia To the Editor: In their interesting study, Ramsay et al demonstrated that plasma adiponectin concentrations are elevated in women with preeclampsia.1 Adiponectin suppressed tumor necrosis factor (TNF)–induced endothelial adhesion molecule expression, macrophage to foam cell transformation, and TNFexpression in macrophage and adipose t...

Leukocyte telomere length and serum levels of high-molecular-weight adiponectin and dehydroepiandrosterone-sulfate (DHEA-S) were assessed in association with nutrition and performance status (PS) in Japanese centenarians. Twenty-three centenarians (five men, 18 women) were classified according to their PS 1 (nearly fully ambulatory, n = 2), 2 (in bed less than 50% of daytime, n = 10), 3 (in bed...

Adiponectin, an adipocyte-derived hormone has been implicated in the control of blood glucose and chronic inflammation in type 2 diabetes. However, limited studies have evaluated dietary factors on plasma adiponectin levels, especially among type 2 diabetic patients in Malaysia. The aim of this study was to investigate the influence of dietary glycemic index on plasma adiponectin concentrations...

Diabetes mellitus caused by insulin resistance is prompted obesity. Neuropeptide Nesfatin-1 was identified in several organs, including the central nervous system and pancreatic islet cells. peptide appears to be involved hypothalamic circuits that energy homeostasis control food intake. Adiponectin a plasma collagen-like protein produced adipocytes have been linked development of (IR), diabete...

Adiponectin circulates in human plasma mainly as a 180-kDa low molecular weight (LMW) hexamer and a high molecular weight (HMW) multimer of approximately 360 kDa. We comprehensively examined the relationships between circulating levels of total adiponectin, adiponectin multimers, and the relative distribution (i.e., ratio) of multimeric forms with key features of the metabolic syndrome. Total a...

BACKGROUND Hypoxic ischemic encephalopathy (HIE) occurs in one to three per 1000 live full-term births. Fifteen to twenty percent will die in the postnatal period, and an additional 25 % will develop severe and permanent neuropsychological sequalae. The control of growth and nutritional status in the fetus and neonate is a complex mechanism, in which also hormones produced by adipose tissue, su...

BACKGROUND Evidence from the literature suggests diminished acetylsalicylic acid (ASA) treatment efficacy in type 2 diabetes (DM2). High on-aspirin platelet reactivity (HAPR) in DM2 has been linked to poor glycemic and lipid control. However, there are no consistent data on the association between HAPR and insulin resistance or adipose tissue metabolic activity. The aim of this study was to ass...