brucellosis is a rare cause of acute acalculous cholecystitis.  we report a 45-year-old, previously healthy, man with brucellosis who presented with abdominal pain due to cholecystitis.

Over one month 103 patients with acute abdominal pain were admitted to the Western Infirmary. Criteria for entry to the study were: (1) no contraindication to the use of potent analgesia or antacid treatment (which might mask important clinical signs); (2) a pain score ¢6 on a visual analogue scalexanging from 0 to 102; and (3) no medical contraindication to the use of potent analgesia. Fifty o...

Anecdotes on the ability of individuals to continue to function under stressful conditions despite injuries causing excruciating pain suggest that acute stress may induce analgesia. However, studies exploring the effect of acute experimental stress on pain perception show inconsistent results, possibly due to methodological differences. Our aim was to systematically study the effect of acute st...

BACKGROUND The study aimed to explore the extent to which NHS acute pain services (APSs) have been established in accordance with national guidance, and to assess the degree to which clinicians in acute pain management believe that these services are fulfilling their role. METHODS A postal questionnaire survey addressed to the head of the acute pain service was sent to 403 National Health Ser...

Clinicians balance the immediate risks and benefi ts of analgesia in infancy, but they also consider the long-term effects of repetitive acute pain against those of prolonged analgesic therapy on brain development. This issue of Pain: Clinical Updates summarizes the current evidence regarding acute pain management in newborns. In 2006, the American Academy of Pediatrics and the Canadian Pediatr...

Generalized hyperalgesia has been demonstrated in cross-sectional studies in a range of chronic pain disorders, including low-back pain. It is not clear, whether the increased sensitivity to experimental pain stimuli in chronic low-back pain sufferers develops early with acute pain, later with chronification, or whether it actually represents pre-existing, high pain sensitivity in a susceptible...

splenic infarction occurs due to occlusion of splenic vessels that leads to splenic tissue ischemia and necrosis. there are several reports regarding splenic infarction in patients with acute myelogenous leukemia (aml). herein, we report a case of acute promyelocytic anemia (aml-m3) who presented with abdominal pain and splenic infarction.

BACKGROUND Acute low back pain is a common condition resulting in pain and disability. Current national and international guidelines advocate general practitioner care including advice and paracetamol (4 g daily in otherwise well adults) as the first line of care for people with acute low back pain. Non-steroidal anti-inflammatory drugs (NSAIDs) and spinal manipulative therapy (SMT) are advocat...