The primary objective of this study was to compare the effectiveness of combination treatment of valproate and amisulpride with that of valproate and haloperidol in bipolar I disorder. Adult inpatients with a current manic episode fulfilling DSM-IV-TR diagnostic criteria for bipolar type I disorder were included. Patients were randomized to amisulpride (400-800 mg/day) or haloperidol (5-15 mg/d...

This paper describes the role of mathematical modelling in the design and evaluation of an automated system of wearable and environmental sensors called PAM (Personalised Ambient Monitoring) to monitor the activity patterns of patients with bipolar disorder (BD). The modelling work was part of an EPSRC-funded project, also involving biomedical engineers and computer scientists, to develop a pro...

Fifty patients of recurrent mania were studied for seasonality of which 11 patients fulfilled our study criteria for Seasonal Affective Disorder (recurrent mania). The two groups of seasonal and nonseasonal recurrent mania were compared on clinical and socio-demographic variables. Results characterised recurrent seasonal mania with psychotic features and occurrence of episodes mainly in summer ...

INTRODUCTION: Bipolar disorder is a recurring chronic characterized by mood, state, and energy fluctuations. Individuals differ in symptoms, course, severity, response to treatment. It critical know the current knowledge of evolving pharmacological psychological strategies bipolar disorder. 
 Primary Objective: To compare assess prescribing pattern psychotropic agents affective with mania ...

BACKGROUND Few studies have analyzed predictors of length of stay (LOS) in patients admitted due to acute bipolar manic episodes. The purpose of the present study was to estimate LOS and to determine the potential sociodemographic and clinical risk factors associated with a longer hospitalization. Such information could be useful to identify those patients at high risk for long LOS and to alloc...