AIM Serological markers for the virus remain mainstay of diagnosis of acute viral hepatitis. However, it is not available in all part of our country. The aim of this study is to find out the sonological findings of the hepatobiliary system that may aid to clinch the diagnosis of acute viral hepatitis. MATERIALS AND METHODS One hundred seventy seven consecutive patients with clinical diagnosis...

Background: Acute viral hepatitis is a common problem in developing countries due to poor hygiene and inadequate sanitation. Biochemical alterations in acute hepaptitis have been well documented in literature. There has been a growing body of evidence in support of the role of inflammation and Reactive oxygen species (ROS) in the pathogenesis of hepatic lesions. Ceruloplasmin is an important ch...

Introduction. Clinical presentation of viral hepatitis ranges from mild symptoms to fulminant hepatitis. Our aim is to describe clinical presentation and outcomes of children with viral hepatitis from the Eastern Ontario/Western Quebec regions of Canada. Methods. Retrospective chart review of children diagnosed with viral hepatitis at our institution from January 1, 1998, to December 31, 2007. ...

Eosinophilic granulomatosis with polyangiitis (EGPA) also known as Churg- Strauss syndrome is a systemic small- and medium-vessel necrotizing vasculitis, characterized by extravascular granulomas, eosinophilia. Treatment primarily corticosteroids and, for severe disease, addition of other immunosuppressive agents. Here, we want to present 57-year-old male patient who was diagnosed EGPA develope...

Pregnant women with acute viral hepatitis are at higher risk of morbidity and death than pregnant women with chronic viral hepatitis. The risk of death is highest with acute viral hepatitis E, and the rate of transmission to the baby may be highest with hepatitis B virus (HBV) infection. Managing viral hepatitis in pregnancy requires assessing the risk of transmission to the baby, determining t...

BACKGROUND Perinatal and horizontal are the common modes of transmission of hepatitis-B virus in children. CASE CHARACTERISTICS Two mother-child pairs with children having received multiple blood transfusions in past. OBSERVATION Both the mothers developed acute hepatitis-B infection whereas children were demonstrated to be having chronic infection with hepatitis-B. OUTCOME One mother cle...

Using the Staphylococcus aureus absorption method, we have modified a commercial radioimmunoassay kit for the determination of total antibody to hepatitis B core antigen so that we can now determine the predominant globulin species of that antibody. One-hundred percent of acute hepatitis B sera had a predominance of immunoglobulin M antibody to hepatitis B core antigen, whereas immunoglobulin G...

Overview Pregnancy is generally considered to be an immunosuppressed state; however, the impact of pregnancy on mothers with viral hepatitis (Table 1) and the impact of viral hepatitis on fetuses/infants (Table 2) are not the same for all types of hepatitis. Pregnant women with acute hepatitis due to hepatitis E virus (HEV) or herpes simplex virus (HSV) have an increased risk of acute liver fai...

51 cases of chronic hepatitis were followed up by serial liver biopsies. 6 cases, all of which were of the active type, showed transition to liver cirrhosis within 5 to 10 months after the initial biopsy which had indicated chronic hepatitis. In 109 cases of liver cirrhosis, the antecedent acute hepatitis had been found within a relatively short period, usually 2 to 3 years before the establish...

BACKGROUND Automatic identification of notifiable diseases from electronic medical records can potentially improve the timeliness and completeness of public health surveillance. We describe the development and implementation of an algorithm for prospective surveillance of patients with acute hepatitis B using electronic medical record data. METHODS Initial algorithms were created by adapting ...