tlte usual manifestation of acute promyelocyte leukemia is hemorrliagic tendency hut thrombotic manifestations may dominate the clinical picture. we report a patient with promyelocyte leukemia which presented as thrombotic cerebrovascular accident and responded to all-transretionic acid and chemotherapy.

background: the innate immunity plays an important role in the host response to transplantation by toll-like receptors and results in development of acute allograft rejection. the aim of this study was to evaluate the association of tlr2 and cd14 (co-receptor) gene polymorphisms with acute rejection in kidney transplant recipients.   methods : the study was conducted in a population of 239 subj...

heparin has an unpredictable pharmacokinetics and the responses of individuals may vary distinctly. therefore, different dosing nomograms have been proposed. the aim of this study was to compare two prevalent nomograms to adjust heparin doses in hospitalized patients with acute coronary syndrome.  one hundred and forty patients received heparin infusions based on one of two nomograms. group 1 r...

background: diseases that cause acute flaccid paralysis (afp) often progress rapidly, thus may cause life threatening complications, therefore, their diagnosis and cure are important. this study was carried out to investigate the causes of acute generalized weakness in children referred to amirkola children’s hospital, in babol, iran. methods: in this case series, the epidemiological causes of ...

background: previous studies have demonstrated the value of serum procalcitonin (pct) as a marker of bacterial infection, as well as the rapid decrease in its concentration with appropriate antibiotic treatment. the aim of this study was to determine the variation in serum pct levels over time during the treatment of acute bacterial meningitis (abm) in adults. methods: in this prospective analy...

the acute toxicity of a malaysian crude oil to red snapper, lutjanus argentimaculatus, blacktiger shrimp and penaeus monodon were investigated. the animals were exposed to water solublefractions (wsf) of crude oil in a flow-through bioassay system and the toxicants were analyzed by gaschromatography (gc) and gas chromatography and mass spectrometer (gc-ms). the 96 h lc50 valuesof the wsf of cru...

to evaluate the prognostic significance of clinicopathological measurement in the diagnosis of acute myocardial infarction (mi) in sheep, acute mi was induced by ligation of left anterior descending coronary artery (lad). for this purpose, twenty four healthy sheep were divided into the sham-operated or control group (group i, thoracotomy without mi) and the experimental group (group ii, with m...

background and purpose: leukemia is the most prevalent type of cancer in children and its prognostic factors vary in different geographic locations. the aim of this study was to estimate the 5 years survival rate of children suffering from leukemia in kerman, iran and to investigate the factors which might influence it. materials and methods: this was a cohort study conducted on patients with a...

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background: we evaluated the efficacy of valproate plus risperidone versus valproate plus lithium combination in the treatment of acute mania. methods: in 2-week, randomized, double-blind, parallel group study, 46 acute manic patients according to dsm-iv criteria were randomly assigned to receive combination of valproate 20 mg/ kg/day plus risperidone 2-4 mg/day (n=23) or lithium600-1200 mg/day...