background: based on literature, in vitro cholesterol removal of lactic acid bacteria has been accounted for their in vivo cholesterol reduction. but recently, it has been proposed that such in vitro characteristic may not be directly relevant to their in vivo activity. the objective of this study was to find how much in vitro cholesterol reducing potential of lactobacillus plantarum a7 (la7), ...

lecithin cholesterol acyltransferase (lcat) plays a major role in the removal of free cholesterol from tissues via assisting hdl-c maturation, and its activity has been proposed as the main indicator of hdl-c function. the aim of the study was to measure lcat activity in type 2 diabetic patients and to elucidate whether lcat is associated with metabolic control, and insulin resistance. a case-c...

background :this study was performed to evaluate the effect of stoppa hernia repair on sexual function of the patients with bilateral inguinal hernia.   methods: in a prospective follow-up study, 50 patients with bilateral inguinal hernia were investigated to assess sexual function before and 1 and 6 months after standardized stoppahernioplasty using the international index of erectile function...

background: knee osteoarthritis is one of the most common disabilities, which may lead to some limitations in physical activity. this study aimed to evaluation of grade one mobilization in improvement of physical function. methods: in this single blind clinical trial with a randomized sampling method, 30 patients of grade two or three, knee osteoarthritis were assigned into three groups: group ...

Objective(s): A newly-introduced protein toxin from a sea anemone, namely fragaceatoxin C is a protein with molecular weight of 20 kDa and pore-forming capability against cell membranes has recently grasped great attentions for its function. In this study, its coding sequence cloned as a fusion protein with His-tag for simple production and rapid purification. Materials and Methods: After PCR a...

we prepared a highly purified and relatively heat stable form of factor viii which contained 25 units per ml (u/ml) activity using peg-4000 and developed an effective and new manufacturing process. heat treatment was performed at 80°c for 72 hrs in the presence of different stabilizers. in our studies, we used different organic solvents as preservatives to maintain factor viii activity, since f...