Monson, R. R. (Harvard School of Public Health, Boston, Mass. 02115). Familial factors in peptic ulcer. I. The occurrence of ulcer in relatives. Amer. 1. Epid., 1970, 97: 453-459—The occurrence of peptic ulcer in relatives of physicians with a history of ulcer has been compared to that in relatives of physicians without ulcer. About twice as many duodenal ulcers as expected occurred in relative...

This study aimed to determine the importance of raised antibodies to Helicobacter pylori in an asymptomatic population. A total of 128 asymptomatic blood donors who were seropositive for H pylori and consented to endoscopy were investigated. These subjects were from a population of 1010 blood donors screened for antibodies to H pylori. A questionnaire was completed to determine if any subjects ...

THE lumen of the first part of the duodenum is a comparatively narrow segment of the alimentary canal so that when the surgeon passes his finger along its length at operation he finds that its mucosa hugs him comfortably. Placing an ulcer into this canal and surrounding its crater by scar tissue would, one might think, produce stenosis in a high percentage of cases, yet the somewhat surprising ...

Besides their traditional food usage, mushrooms can be used as a source of many pharmacologically active compounds, especially polysaccharides. Wastes left over in the edible mushroom farms such as Agaricus bisporus (white button mushroom) can also become free and alternative source of chitin-chitosan materials, beside the traditional industrial source shellfish waste materials. Chitosan, a nat...

The 24-hour excretion of 17-ketosteroids and 17-hydroxycorticosteroids has been estimated in a series of male duodenal ulcer subjects and compared with that of 56 normal male controls. It has been found that both 17-ketosteroid and 17-hydroxycorticosteroid excretion is less in ulcer subjects than in the control group; these differences are not large but in the case of 17-hydroxycorticosteroids ...

BACKGROUND The treatment for the eradication of Helicobacter pylori (H. pylori) is complex; full effectiveness is rarely achieved and it has many adverse effects. In developing countries, increased resistance to antibiotics and its cost make eradication more difficult. Probiotics can reduce adverse effects and improve the infection treatment efficacy.If the first-line therapy fails a second-lin...

Intoduction: Neuropathic plantar ulceration is one of the serious handicap to the patient with anaesthetic feet in active life. The only way to heal a plantar ulcer is to provide rest it. If the patient walks on the ulcer,it spreads and osteomyelitis ensues; the scarring and distortion make further inevitable ulceration until walking finally becomes impossible.Neuropathic trophic plantar ulcera...

Thirteen patients are described who, on routine endoscopy of the upper gastrointestinal (GI) tract, were found to show a characteristic appearance in the proximal duodenum. This consisted of multiple small mucosal nodules, predominantly in the anterior wall. All cases were biopsied, and showed identical histological appearances of heterotopic gastric mucosa of body type. The incidence of this c...

Mycolactone is a polyketide natural product secreted by Mycobacterium ulcerans, the organism responsible for the tropical skin disease Buruli ulcer. The finding that this small molecule virulence factor is sufficient to reconstitute the necrotic pathology associated with Buruli ulcer suggests that a better understanding of mycolactone biosynthesis, particularly the processes which are distinct ...