Preserving skin microbiota homeostasis is of crucial importance for maintaining healthy skin. We have developed a new active ingredient from Bombax costatum flowers, this polysaccharide-rich extract was evaluated in vitro on models using different bacterial strains representative cutaneous (S. aureus, S. epidermidis, hominis, C. acnes). The significantly increased keratinocyte production innate...

The present study reports the results obtained after analysis of thermal stability and decomposition kinetics widely used synthetic derivative estradiol, ethinylestradiol (EE), as a pure active pharmaceutical ingredient. As investigational tools, Fourier transformed infrared spectroscopy (FTIR), analysis, modeling EE were employed. kinetic was realized using three methods, namely Kissinger, Fri...

A simple and accurate reverse phase liquid chromatographic method was developed for the determination of related substances, degradants and assay of Tolterodine Tartarate active pharmaceutical ingredient used in the treatment of urinary incontinence. A HPLC method was developed for the separation of related substances, degradants obtained from samples generated after stress degradation and also...

The nontarget effects of temephos (as Abate 4E, 44.6% active ingredient) on fiddler crabs were examined on the salt marsh at Bombay Hook National Wildlife Refuge, near Dover, DE. Six 170 x 170-m plots were established; 3 were sprayed on 4 occasions at a rate of 1.5 fl oz/acre (0.054 kg active ingredient/ha) and 3 were controls. On each plot, marsh fiddler crab (Uca pugnax) populations were moni...