In this paper we aim to characterize association schemes all of whose symmetric fusion schemes have only integral eigenvalues, and classify those obtained from a regular action of a finite group by taking its orbitals.

The design of phase I studies is often challenging, because of limited evidence to inform study protocols. Adaptive designs are now well established in cancer but much less so in other clinical areas. A phase I study to assess the safety, pharmacokinetic profile and antiretroviral efficacy of C34-PEG4 -Chol, a novel peptide fusion inhibitor for the treatment of HIV infection, has been set up wi...

An experimental search for nuclear fusion inside imploding bubbles of degassed deuterated acetone at 0 degrees C driven by a 15 atm sound field and seeded with a neutron generator reveals an upper bound that is a factor of 10 000 less than the signal reported by Taleyarkhan et al. The strength of our upper bound is limited by the weakness of sonoluminescence, which we ascribe to the relatively ...

based on a meta-theoretical analysis of voting, the present paper is an attempt to present a theoretical model encompassing all the possible aspects of voting in an election action system, proposing four sub-systems of voting as follows: economic voting, political voting, cultural voting and moral voting. having distinguished among these sub-systems, the writer describes the constitutive elemen...

AS160 (TBC1D4) is a known Akt substrate that is phosphorylated downstream of insulin action and that leads to regulated traffic of GLUT4. As GLUT4 vesicle fusion with the plasma membrane is a highly regulated step in GLUT4 traffic, we investigated whether AS160 and 14-3-3 interactions are involved in this process. Fusion was inhibited by a human truncated AS160 variant that encompasses the firs...

Identity fusion is a visceral sense of “oneness” with a group and its individual members that motivates personally costly, pro-group behaviors. Past approaches, most notably social identity theory, have assumed that when people align with groups, the group category eclipses both the personal self and the relationships among individual group members. Also, social identity researchers have focuse...

Membrane active peptides can perturb the lipid bilayer in several ways, such as poration and fusion of the target cell membrane, and thereby efficiently kill bacterial cells. We probe here the mechanistic basis of membrane poration and fusion caused by membrane-active, antimicrobial peptides. We show that the cyclic antimicrobial peptide, BPC194, inhibits growth of Gram-negative bacteria and ru...

Dictyostelium cells that lack a functional myosin II heavy chain are motile and are capable of aggregation, but fail to undergo further multicellular development. We have used a Dictyostelium mutant expressing a cold-sensitive myosin heavy chain to examine the requirement for myosin throughout the course of development. The loss of myosin function upon cooling is rapid and reversible. Temperatu...

Current models for membrane fusion in diverse biological processes are focused on the local action of fusion proteins present in the contact zone where the proteins anchored in one membrane might interact directly with the other membrane. Are the fusion proteins outside of the contact zone just bystanders? Here we assess the role of these "outsider" proteins in influenza virus hemagglutinin-med...

Two main humanitarian mine action types may benefit from multi-sensor data fusion techniques: 1) close range antipersonnel (AP) mine detection and 2) mined area reduction. Data fusion for these two applications is presented here. Close range detection consists of detection of (sub-)surface anomalies that may be related to the presence of mines (e.g., detection of metals using a metal detector, ...