BACKGROUND & OBJECTIVE Lichen planus is a mucocutaneous disease which is relatively common and in 30-70% of patients, mucosal lesions can be seen and known as a precancerous lesion but its etiology is not completely understood. Desmogleins I and III are the main desmosomal transmembrane proteins. These proteins have been identified as the autoantigen of the autoimmune disease. The aim of this s...

OBJECTIVE(S) Lichen Planus is a common disease with unknown etiology which affects the skin and mucosa. Recent studies have focused on the possible role of the virus in the pathogenesis of Lichen Planus. The purpose of this study was to determine the association between the human T-cell lymphotropic virus type 1 and Lichen Planus. MATERIALS AND METHODS This case control study was conducted on...

IMPORTANCE Lichen planus is an autoimmune inflammatory dermatosis that typically affects the skin but can also involve the stratified squamous epithelium of the external auditory canals and tympanic membranes. Here we report our experience with the clinical presentation, diagnosis, and management of otic lichen planus. OBSERVATIONS We retrospectively reviewed medical records from January 1, 2...

Lichen planus of the male genitalia presents as multiple violaceous papules or discrete annular lesions on the glans or shaft of the penis. In female patients, whitish striae or "leukoplakia-like" patches are occasionally observed on the vestibulum or labia minora and bluish-white papules in the anal cleft or around the anus. Signs of lichen planus elsewhere on the body may be absent. As has be...

background: oral lichen planus is a chronic inflammatory disease with a poorly understood etiology. the role of angiogenesis in the development of different chronic inflammatory diseases is of great concern. vascular endothelial growth factor (vegf) is an important regulator of angiogenesis. we aimed to evaluate the serum level of vegf in patients with oral lichen planus compared with normal in...

background and aims. the purpose of this study was to determine efficacy of 19% elaeagnus angustifolia (ea) topical gel in the treatment of symptomatic oral lichen planus. materials and methods. patients with symptomatic oral lichen planus referring to the department of oral medicine, faculty of dentistry at shahid beheshti university of medical sciences were asked to participate in the study. ...

BACKGROUND AND AIMS Oral lichen planus (OLP) is a common chronic mucocutaneous disease. Patients with atrophic and erosive lichen planus often have symptoms of soreness and need proper treatment. The main therapy of OLP has been the administration of topical or systemic corticosteroids. Potent topical corticosteroids have been increasingly prescribed in the treatment of erosive lichen planus. T...

AIM Many studies have suggested that a lesion originally diagnosed as oral lichen planus (OLP) has different possibilities of undergoing malignant transformation in time, although these findings remain a controversial issue; for example, some studies reported different values of potential malignancy of OLP. INTRODUCTION World Health Organization (WHO) classifies OLP as a "potentially malignan...

Ashy dermatosis, also known as erythema dyschromicum perstans, is an idiopathic dermal melanosis of unknown etiology. We here describe an unusual case of 63-year-old Caucasian male with ashy dermatosis and skin lesion of lichen pigmentosus-like. No treatment was tried because the lesions were totally asymptomatic. After a control, three months later, all lesions had cleared up. This case is of ...

Lichen planus is a relatively common mucocutaneous lesion in adults but it rarely seen paediatric patients. Here we presenting case of oral lichen 10 years old boy. The diagnosis was made on the basis clinical features only. Topical steroid therapy most given planus. This wastreated with novel treatment modality topical tacrolimus 0.03% and patient responded well to treatment.