Epinephrine is recommended in contemporary educational efforts by the American Heart Association (AHA) as central to adult Advanced Cardiac Life Support (ACLS). However, International Liaison Committee on Resuscitation (ILCOR) 2019 recommendations update describes large evidentiary gaps for epinephrine use cardiopulmonary resuscitation, highlighting that clinical and experimental evidence do no...

Introduction: Advanced Cardiac Life Support (ACLS) course is one of the mandatory certifications for majority medical as well some nursing professionals. There are, however, multiple variations in its instruction model worldwide. We aim to evaluate efficacy traditional ACLS versus a hybrid utilised during COVID-19 pandemic. Methods: This retrospective study was carried out at SingHealth Duke-NU...

OBJECTIVE Advanced airway management is one of the fundamental skills of advanced cardiac life support (ACLS). A failed initial intubation attempt (FIIA) is common and has shown to be associated with adverse events. We analysed the association between FIIA and the overall effectiveness of ACLS. METHODS Using emergency department (ED) out-of-hospital cardiac arrest (OHCA) registry data from 20...

OBJECTIVE Because the percentage of missing portion sizes was large in the Aerobics Center Longitudinal Study (ACLS), careful consideration of the accuracy of standard portion sizes was necessary. The purpose of the present study was to investigate the consequences of using standard portion sizes instead of reported portion sizes on subjects' nutrient intake. METHODS In 2307 men and 411 women...

BACKGROUND Early countershock of ventricular fibrillation has been shown to improve immediate and long-term outcome of cardiac arrest. However, a number of investigations in the laboratory and in the clinical population indicate that immediate countershock of prolonged ventricular fibrillation most commonly is followed by asystole or a nonperfusing spontaneous cardiac rhythm, neither of which r...

Loss of function mutations of Kif7, the vertebrate orthologue of the Drosophila Hh pathway component Costal2, cause defects in the limbs and neural tubes of mice, attributable to ectopic expression of Hh target genes. While this implies a functional conservation of Cos2 and Kif7 between flies and vertebrates, the association of Kif7 with the primary cilium, an organelle absent from most Drosoph...

Access-Control Lists (ACLs) (a.k.a. friend lists) are one of the most important privacy features Online Social Networks (OSNs) as they allow users to restrict audience their publications. Nevertheless, creating and maintaining custom ACLs can introduce a high cognitive burden on average OSNs since it normally requires assessing trustworthiness large number contacts. In principle, community dete...