Solid organ transplant recipients (OTRs) have an increased incidence of skin cancer, resulting in significant morbidity and mortality post-transplantation. Chemoprevention strategies are focused on reducing and delaying the development of skin cancer in these patients. Although systemic retinoids are widely used in OTRs, few randomized controlled trials have been performed. Limited data suggest...

With the institution of antiretroviral therapy, psoriasis can be controlled with topical treatments, such as clobetasol and calcipotriene and ultraviolet light. Before adequate immune reconstitution under antiretroviral therapy occurs or in cases of complex or more severe psoriasis, treatment with the retinoid agent acitretin at 10 to 25 mg/d can be considered; it should be noted that this agen...

Journal Compilation © 2011 Acta Dermato-Venereologica. ISSN 0001-5555 Perifolliculitis capitis abscedens et suffodiens (PCAS) is a rare scalp disease seen mostly in young males of Afro-American descent. The disease is characterized by perifollicular pustules, suppurative nodules and fluctuating abscesses, as well as by intercommunicating sinus tracts on the scalp. We report here an elderly Cauc...

Epidermolytic hyperkeratosis is a form of ichthyosis normally resistant to topical treatments. Female patient monitored since 1978 diagnosed with epidermolytic hyperkeratosis. Clinical examination showed generalized hyperkeratosis and scaling. Given that no other treatments were available at the time, the patient was initially treated with keratolytic, systemic vitamin A and moisturizers, with ...

A 65-year-old woman with palmoplantar psoriasis was referred with intense itching eczematous dermatitis on her feet. Her history showed that she had her psoriasis treated for 3months with oral acitretin 0.5mg/kg daily and daily topical application of an emollient stick used to improve the re-epithelization of fissured heels. During the treatment, her hands healed quickly, but she experienced wo...

Lichen amyloidosus Retinoids Apoptosis Norbert Reider, MD, Department of Dermatology, University of Innsbruck, Anichstrasse 35, A-6020 Innsbruck (Austria) In September 1993, a 72-year-old woman presented at our Department with an eruption of reddish brown, coalescent, hyperkeratotic, extremely pruritic papules of her thighs (fig. 1), the extensor surfaces of both forearms and the lumbosacral ar...

Lipoid proteinosis (LP) is an extremely rare autosomal recessive genodermatosis, characterized by persistent hoarseness and classical skin lesions. Amorphous hyaline depositions may affect any organ, but mainly the face extremities. These cause limitations in tongue movement, hence, difficulty speaking. Biopsies of lesions usually show massive deposits homogeneous, acidic, hyaline-like material...