نتایج جستجو برای: acarbose

تعداد نتایج: 915  

2014
Nisa M. Maruthur Matthew O. Gribble Wendy L. Bennett Shari Bolen Lisa M. Wilson Poojitha Balakrishnan Anita Sahu Eric Bass W.H. Linda Kao Jeanne M. Clark

OBJECTIVE We performed a systematic review to identify which genetic variants predict response to diabetes medications. RESEARCH DESIGN AND METHODS We performed a search of electronic databases (PubMed, EMBASE, and Cochrane Database) and a manual search to identify original, longitudinal studies of the effect of diabetes medications on incident diabetes, HbA1c, fasting glucose, and postprandi...

2012
Christian Díaz de León-Castañeda Marina Altagracia-Martínez Jaime Kravzov-Jinich Ma del Rosario Cárdenas-Elizalde Consuelo Moreno-Bonett Juan Manuel Martínez-Núñez

INTRODUCTION Worldwide, diabetes mellitus presents a high burden for individuals and society. In Latin America, many people with diabetes have limited access to health care, which means that indirect costs may exceed direct health care cost. Diabetes is Mexico's leading cause of death. PURPOSE To evaluate the cost-effectiveness ratios of the most used oral hypoglycemic agents (OHA) in the tre...

Journal: :American journal of physiology. Endocrinology and metabolism 2001
A Salehi B G Fan M Ekelund G Nordin I Lundquist

We examined the relation between nutrient-stimulated insulin secretion and the islet lysosome acid glucan-1,4-alpha-glucosidase system in rats undergoing total parenteral nutrition (TPN). During TPN treatment, serum glucose was normal, but free fatty acids, triglycerides, and cholesterol were elevated. Islets from TPN-infused rats showed increased basal insulin release, a normal insulin respons...

2018
Warren Ladiges Denny Liggitt

Aging is a complex multifactorial process, meaning that multiple pathways need to be targeted to effectively prevent or slow aging [1]. A number of molecular pathways are well known for influencing aging, but only a few have been successfully targeted with individual drugs, and these drugs do not individually target all aging pathways. However, combinations of these drugs might have the potenti...

2013
Leila Moradabadi Shideh Montasser Kouhsari Mohammad Fehresti Sani

Garlic (Allium sativum L., Alliaceae), Persian shallot (Allium ascalonicum L., Alliaceae ) and Sage (Salvia officinalis L., Lamiaceae) are believed to have hypoglycemic properties and have been used traditionally as antidiabetic herbal medicines in Iran. In this study, diabetes was induced by subcutaneous injection of alloxan monohydrate (100 mg kg(-1)) to male Wistar rats. Antidiabetic effects...

Journal: :Pakistan journal of pharmaceutical sciences 2015
Saifullah Mehsud Musarrat Rauf - Obaidullah Kamran Ahmad Khan Gul Majid Khan

The aim of the study presented is to formulate and evaluate Acarbose controlled release matrix tablets by means of different grades of polymer Ethocel and different co-excipients with the intention to see their effects on drug release profile during in vitro dissolution studies. Controlled release dosage forms is gaining rapid popularity due to its positive aspect of reduction in dosage frequen...

Garlic (Allium sativum L., Alliaceae), Persian shallot (Allium ascalonicum L., Alliaceae ) and Sage (Salvia officinalis L., Lamiaceae) are believed to have hypoglycemic properties and have been used traditionally as antidiabetic herbal medicines in Iran. In this study, diabetes was induced by subcutaneous injection of alloxan monohydrate (100 mg kg−1) to male Wistar rats. Antidiabetic effects of...

Anitha Roy, Devaraj Ezhilarasan Rajesh Nivesh Krishna

Objective: Tamarindus indica Linn.(T.indica) is a well-known plant used in traditional medicine. The plant is popular for its antidiabetic activity. However, effect so f its aqueous fruit pulp extract on carbohydrate hydrolyzing enzymes and its glucose uptake potential were not explored. Materials and Methods: The antidiabetic activity w...

M Teimori , R Ghafarzadegan , R Hajiaghaee , S Montasser Kouhsari ,

  Background: Hypoglycemic effect of Juglans regia leaves was reported in other previous researches.   Objective: To investigate the mechanism of hypoglycemic action of Julans regia Leaves Methanolic Extract (JRLME), we designed the following study.   Methods: Male wistar rats were classified in five groups, each of six, including alloxan-induced diabetic rats treated with JRLME at doses of 250...

Journal: :Nova Biotechnologica et Chimica 2021

The antioxidant and hypoglycemic capacities of various solvent fractions from the trunk-bark methanol extract Terminalia alata Heyne ex Roth (T. alata) were investigated. DPPH radical scavenging assay was used to evaluate activity, methods for determination digestive enzymes inhibitory activity fasting blood glucose reduction capacity in diabetic rats determine fractions. results indicated that...

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