The biomarker "ischemia-modified albumin" (IMA), measured by the albumin-cobalt-binding assay (ACB assay), is the only FDA-approved biomarker for early diagnosis of myocardial ischemia. On the basis of the hypothesis that high levels of free fatty acids are directly responsible for reduction in cobalt binding by albumin, chemically defined model systems consisting of bovine serum albumin, Co(2+...

A novel and easily accessible luminescent iridium(iii) complex [Ir(tpy)2(N^N)]PF6 (, tpy = 2-(p-tolyl)pyridine, N^N = 4-[(4-amino-3-nitrophenoxy)-methylene]-4'-methyl-2,2'-bipyridine) for the sensing of HOCl has been designed and synthesized. The detection strategy is based on the HOCl-promoted cleavage of the PET quenching 4-amino-3-nitrophenyloxy moiety of the weakly emissive complex , which ...

polyethylene imide was synthesized from the reaction of high density polyethylene grafted maleic anhydride (pe-g-ma) and 1,4-diaminobutane in boiling xylene. the chemical compositions of the reaction products were examined by fourier transform infrared spectroscopy. different conditions and parameters like the effect of temperature, time, monomer concentration and oxygen on the extent of reacti...

OBJECTIVE To examine the effect of dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, on the major components of renal glucose reabsorption (decreased maximum renal glucose reabsorptive capacity [TmG], increased splay, and reduced threshold), using the pancreatic/stepped hyperglycemic clamp (SHC) technique. RESEARCH DESIGN AND METHODS Subjects with type 2 diabetes (n=12) and m...

Sodium-glucose cotransporter 2 (SGLT2) inhibitors showed a glucose lowering effect in type 2 diabetes patients through inducing renal glucose excretion. Detailed analysis of the mechanism of the glucosuric effect of SGLT2 inhibition, however, has been hampered by limitations of clinical study. Here, we investigated the mechanism of urinary glucose excretion using nonhuman primates with SGLT inh...

This article has as goal to discuss the importance of Intellectual Capital’s management obtain positive results from investments Human Capital sector Resources institutions a private administrative nature and check what generates more in Capital: investment human resources for titration or new ways Capital. From reach these goals, problem will be answered: How terms Capital? The hypothesis that...

The study of 14 normal young men by glucose titration procedures has defined the magnitude of splay in this population, differing from previously reported data in its unexpected deviation from the line of theoretic unity high on the titration curve. Compared to these normal subjects, a group of glucosuric men could be divided into two subclasses, those with normal maximal rate of glucose reabso...

background and objectives: vaccination is the major strategy to protect nurses against infection with hepatitis b virus. however, some nurses do not produce sufficient amount of anti-hbsag antibody required for immunity against infection. chronic occupational stress has been proposed as a risk factor to humoral immunity. given that nursing staff is exposed to occupational stress risk, this stud...

Anemonia sulcata purple protein (asFP595) belongs to a family of green fluorescent protein (GFP)-like proteins from the Anthozoa species. Similar to GFP, asFP595 apparently forms its chromophore by modifying amino acids within its polypeptide chain. Until now, the GFP-like proteins from Anthozoa were thought to contain chromophores with the same imidazolidinone core as GFP. Mass spectral analys...