We describe a new publicly available algorithm for identifying absent sequences, and demonstrate its use by listing the smallest oligomers not found in the human genome (human "nullomers"), and those not found in any reported genome or GenBank sequence ("primes"). These absent sequences define the maximum set of potentially lethal oligomers. They also provide a rational basis for choosing artif...

This commentary refers to the article, Absent fetal hand: a case report, published in Australasian Journal of Ultrasound in Medicine May 2010 13 (2). This case raises difficult ethical issues about the use of medical imaging in pregnancy, including the role that a diagnosis of foetal disability or abnormality should play in decisions about late terminations. In Australia, late termination is ty...

This paper attempts to put the research on human rationality into proper context by looking at it across disciplines and by identifying the main questions that propelled research in di erent elds. Experimental psychology produced many results that need to be evaluated critically for a complete understanding of the concept. The present paper presents some of these numerous ndings, but mostly foc...

This study investigated 7-month-old infants' ability to relate vowel sounds with objects when intersensory redundancy was present versus absent. Infants (N = 48) were habituated to two alternating video-films of vowel-object pairs in one of three conditions. In the moving-synchronous condition, where redundancy was present, the movement of one object was temporally coordinated with the spoken v...

The clinical, haematological and biochemical findings, treatment and outcome of 63 cows with haemorrhagic bowel syndrome are described. The general condition and demeanor were moderately to severely abnormal in all the cows. Signs of colic occurred in 27 cows, decreased rectal temperature in 46 and tachycardia in 44. With the exception of one cow, intestinal motility was decreased or absent. Tr...

Theories on neural compensation suggest that aged participants overactivate the brain areas involved in a task to compensate for the age-related decline. In this electrophysiological study, we investigated the temporal locus of neural overactivation in aging during multiple target processing. We measured performance and three event-related brain potential responses (N1, N2pc, and contralateral ...

Electrophysiological measurements were taken from observers performing a visual search within a single feature dimension, and between multiple dimensions. The N2pc to selected singleton target stimuli (rightward tilted lines) was increased when targets varied between feature dimensions, compared to the N2pc to the same rightward tilted line targets, in a condition in which targets varied only b...

Arthrogryposis multiplex congenita is a heterogeneous condition and many different types are clinically recognisable. Recently, a new type of autosomal dominant arthrogryposis was described in a father and son. We report on a male patient with similar clinical features, confirming this distinct type of arthrogryposis. The condition is characterised by congenital contractures of the hands and fe...

This article presents a method for estimating the accuracy of psychological screening scales using receiver operating characteristic curves and associated statistics. Screening scales are typically semicontinuous within a known range with distributions that are nearly symmetric when the target condition is present and highly skewed when the condition is absent. We model screening scale outcomes...