The present study aimed to evaluate the GSH and MDA levels in dog’s serum vital organs of aborted fetuses, after application two abortifacient. Animals group I (n = 6) were treated twice with subcutaneous injection 10 mg/kg aglepristone II 3) received prostaglandin F2α at a dose 125 μg/kg every 12 hours until abortion process completed. Hematologic examinations sedimentation rates performed bit...

BACKGROUND The systematic analysis of morbidity and mortality for the Food and Drug Administration (FDA)-approved medical abortion regimen using mifepristone is possible using data from the FDA's Adverse Event Reporting System. OBJECTIVE To assess mifepristone's mortality, morbidity, sentinel events, and quality of postmarketing surveillance using mifepristone adverse event reports (AERs). ...

We have used the forward mutation to resistance to 6 azauracil to test the mutagenicity of rivanol (6,9 diamino 2-ethoxy acridine) on Escherichia coli. Rivanol has been used to induce therapeutic abortions in midpregnancy and is considered safe and effective for this purpose. The findings reported here that rivanol, like other acridines, is a mutagen, at least in procaryotes, suggests that such...

Isocupressic acid (ICA) [15-hydroxylabda-8 (17), 13E-dien-19-oic acid], a labdane diterpene acid, isolated from ponderosa pine (Pinus ponderosa), Lodgepole pine (Pinus contorta), common juniper (Juniperus communis) and Monterey cypress (Cupressus macrocarpa), induces abortion in pregnant cows when ingested primarily during the last trimester. The objective of this study was to investigate the e...

The present report describes and offers a discussion of experiments that deal with the observations of Elsasser and Wallace,2 who have stated inscience: " I t would seem, then, that the urine and serum of patients with malignan't tumors have a selective destructive action on embryonal or newly growing tissue." These investigators briefly described an abortifacient action in pregnant rabbits pro...

Objective: Peganum harmala (P. harmala), “Espand” in Persian, has small seeds and has been used in traditional medicine as emmenagogue and an abortifacient. It has various pharmacological effects such as antifungal, antibacterial, hypothermic, anticancer, antinociceptive, and reversible monoamine oxidase inhibition. Case details: This case was a 45 years old woman who ingested about 50 grams se...

The e ffect of chloroquine on the responses of smooth, cardiac and skeletal muscles to various drugs have been investigated using small laboratory animal3 such as guinea pigs, rats and rabbits. In a ll cases, isolated tissues were used. In addition, the e ffec t of intraperitoneal ( IP ) administration o f chloroquine on pregnant rats was undertaken, to investigate its alleged abortifacient act...