The crossmatch has been used as the final phase of pretransfusion testing for over half a century.’ However, during this time, there have been frequent modifications of the procedure, as well as differences of opinion as to the extent of its performance. In recent years, modifications have focused on its abbreviation. When the American Association of Blood Banks first published its standards in...

Aim: Indirect neonatal hyperbilirubinemia is a common disorder worldwide which can remain benign if prompt management available. However there higher morbidity and mortality risk in settings with limited access to diagnosis care. The aim of this study was evaluate the etiologies indirect hyperbilirubinemia, determine effectiveness phototherapy treatment specify associated factors for prolonged ...

The discovery of ABO(H) blood group antigens resulted in the birth of transfusion medicine and allowed for the first time the use of a laboratory test that could predict immunologic outcomes prior to transfusion. Although ABO(H) antibody testing continues to represent one of the first and most common examples of personalized medicine, it was not until many years later that the existence of non-...

Blood groups A, B, and O were described by Landsteiner in 1901 and the serological crossmatch between the blood donor and the recipient, as a means of preventing ABO incompatibility, was first described by Ottenberg in 1908. In 1941, Rh antibodies were found to be the cause of haemolytic disease of the newborn. The earliest detected forms of anti-D antibodies were very strong and found by salin...

Although ABO incompatibility between mother and the conceptus has long been suspected as a cause of spontaneous abortion in man its precise contribution has not been completely resolved (Levene and Rosenfield, 1961). In spite of reports in which the incompatible mating was recognized to be a cause ofhabitual abortion (McNeil et al, 1954) and which eventually results in infertility (Behrman et a...