نتایج جستجو برای: abcc1
تعداد نتایج: 519 فیلتر نتایج به سال:
Chamomile tea is a popular beverage and herbal remedy with various health benefits, including antioxidant antimicrobial activities beneficial effects on metabolism. In this study, we investigated the inhibitory of secondary metabolites from Matricaria chamomile L. against COX2, an enzyme involved in inflammation linked to cancer development. The cytotoxicity compounds was also evaluated panel 6...
The phenomenon of multidrug resistance (MDR) has decreased the hope for successful cancer chemotherapy. The ATP-binding cassette (ABC) transporter superfamily is the largest transmembrane family. The overexpression of ABC transporters is a major determinant of MDR in cancer cells both in vitro and in vivo. Unfortunately, until recently, most of the strategies used to surmount ABC-transporter-me...
Multidrug resistance (MDR) to chemotherapeutic drugs is a formidable barrier to the success of cancer chemotherapy. Expressions of ATP-binding cassette (ABC) transporters contribute to clinical MDR phenotype. In this study, we found that afatinib, a small molecule tyrosine kinase inhibitor (TKI) targeting EGFR, HER-2 and HER-4, reversed the chemoresistance mediated by ABCG2 in vitro, but had no...
SINCE 1958, the Atomic Bomb Casualty Commission (ABCC) has been conducting a long-term follow-up investigation (Adult Health Study) [ 1] of large defined population samples in Hiroshima and Nagasaki, Japan. In the course of this program the prevalence of definite rheumatoid arthritis was measured and its incidence estimated, according to observations made upon 16,269 subjects from 1958 to 1964 ...
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