BACKGROUND Two randomised, double-blind, placebo-controlled trials have investigated the efficacy of IV alpha-1 antitrypsin (AAT) augmentation therapy on emphysema progression using CT densitometry. METHODS Data from these similar trials, a 2-center Danish-Dutch study (n = 54) and the 3-center EXAcerbations and CT scan as Lung Endpoints (EXACTLE) study (n = 65), were pooled to increase the st...

STUDY OBJECTIVE The purpose of this study was to compare the imaging findings of nontuberculous mycobacterial (NTM) infection in patients with normal and abnormal cystic fibrosis (CF) genotypes, and normal and abnormal alpha1-antitrypsin (AAT) phenotypes. DESIGN A retrospective review of medical records and chest CT scans from 85 patients with microbiologically proven NTM infection was perfor...

Approach biases to foods may explain why food consumption often diverges from deliberate dietary intentions. Yet, the assessment of behavioural with approach-avoidance tasks (AAT) is unreliable and validity partially unclear. The present study continues a series studies that develop task based on naturalistic approach avoidance movements touchscreen (hand-AAT). In hand-AAT, participants ...

Soybean (Glycine max (L.) Merr.) is a typical short-day and thermophilic crop. This study aimed to reveal the required accumulative day length (ADL) active temperature (AAT) for DSF (days of sowing flowering) DFM flowering maturity) in global soybeans. A sample consisted 354 varieties from 27 countries five geographic regions, which were tested Nanjing, China two spring-sowing summer-sowing sea...

To study further the role of intermediate alpha1-antitrypsin (AAT) deficiency in chronic obstructive pulmonary disease (COPD), AAT Pi-types and serum.trypsin-inhibitory-capacity (STIC) were measured in 965 patients th CQPD. Heterozygosity of the Z variant was the major cause of intermediate AAT deficiency (primarily the MZ phenotype), accounting for 8.0 percent of the patients compared to 2.9 p...

We recently reported that aspartate (Asp) biosynthesis in plant chloroplasts is catalyzed by two different Asp aminotransferases (AAT): a previously characterized eukaryote type and a prokaryote type (PT-AAT) similar to bacterial and archaebacterial enzymes. The available molecular and kinetic data suggest that the eukaryote-type AAT is involved in the shuttling of reducing equivalents through ...

BACKGROUND The aim of this study was to evaluate the efficacy of animal-assisted therapy (AAT) in elderly patients affected by Alzheimer's disease based on the formal reality orientation therapy (ROT) protocol. METHODS Our study was carried out at an Alzheimer's centre for 6 months. A homogeneous sample (age, Mini-Mental State Examination (MMSE), 15-item Geriatric Depression Scale (GDS)) of 5...