نتایج جستجو برای: aaph

تعداد نتایج: 218  

Journal: :Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2007
Ganesh Rajaraman Guqi Wang Howard J Smith Yu Gong Frank J Burczynski

PURPOSE We investigated a potential hepatoprotective role of d-cis diltiazem, l-cis diltiazem, thiamine and the combination d-cis diltiazem and thiamine against lipid peroxidation in a piglet liver microsomal model. A modified in vitro dichlorofluorescein assay was developed to assess the extent of peroxidative damage induced by reactive oxygen species in the piglet liver microsomal fraction. ...

2017
Norma Julieta Salazar-López Gustavo A González-Aguilar Guadalupe Loarca-Piña Francisco J Cinco-Moroyoqui Ofelia Rouzaud-Sández J Abraham Domínguez-Avila Maribel Robles-Sánchez

An imbalance between free radicals and antioxidants is known as oxidative stress, and it promotes cellular aging and the development of chronic noncommunicable diseases. The bioactive compounds present in food play an important role in preventing oxidative stress. The aim of this study was to determine the contributions and interactions of the hydroxycinnamic acids found in the bran and whole g...

Journal: :Biological & pharmaceutical bulletin 2008
Tetsuo Watanabe Yuki Nakajima Tetsuya Konishi

Basidiomycetes-X (BDM-X) is a novel edible mushroom recently identified as a new fungi species and registered to the database of the NPO organization for International Patent Organism Depositing (IPOD) in the Industrial Technology Institute of Japan (PCT/JP2004/006418). In the present study, we examined anti-oxidant activity of hot water extract of this novel fungus both in vitro and in vivo to...

Journal: :International journal of molecular medicine 2008
Dae Youn Hwang Ji Soon Sin Min Sun Kim Su Youn Yim Yong Kyu Kim Chuel Kyu Kim Byoung Guk Kim Sun Bo Shim Seung Wan Jee Su Hae Lee Chang Joon Bae Byoung Chun Lee Mee Kyung Jang Jung Sik Cho Kab Ryong Chae

Selenoprotein is associated with a variety of serious diseases, including infectious diseases, neurodegenerative disorders, cancer and cardiovascular disease. The aim of this study was to produce a new transgenic (Tg) rat expressing human selenoprotein M (SelM) in order to examine the protective function of the antioxidant status in vivo. To achieve this, a new lineage of Tg rats was produced b...

Journal: :Molecules 2011
Kuo-Ching Wen Hua-Hsien Chiu Pei-Ching Fan Chien-Wen Chen Shih-Mei Wu Jung-Hsiang Chang Hsiu-Mei Chiang

Polyphenols and flavonoids possess a variety of biological activities including antioxidant and anti-tumor activities. Ixora parviflora is a member of the flavonoid-rich Rubiaceae family of flowering plants and used as folk medicine in India. The aim of this study was to investigate the antioxidant activity of Ixora parviflora extract (IPE) in a cell-free system and erythrocytes, and the abilit...

Journal: :Life sciences 1997
A Zhang Q Y Zhu Y S Luk K Y Ho K P Fung Z Y Chen

Jasmine green tea is an excellent source of natural polyphenol antioxidants including mainly (-) epicatechin (EC), (-) epicatechin gallate (ECG), (-) epigallocatechin (EGC) and (-) epigallocatechin gallate (EGCG). The present study was to test our hypothesis that ingestion of jasmine tea would protect red blood cell (RBC) membrane from free radical-induced oxidation if jasmine tea epicatechin i...

Journal: :Molecules 2010
H P Vasantha Rupasinghe Afsana Yasmin

The antioxidant properties of two apple dihydrochalcones, namely phloretin and phloridzin, were evaluated and compared with those of alpha-tocopherol and butylated hydroxytoluene (BHT). The effects were studied in an oil-in-water emulsion system containing methyl linolenate (ML), methyl eicosapentaenoate (MEPA), and methyl docosahexaenoate (MDHA) in which oxidation was initiated by the peroxyl ...

2013
Hsiu-Mei Chiang Hsin-Chun Chen Hua-Hsien Chiu Chien-Wen Chen Ssu-Meng Wang Kuo-Ching Wen

In this study, we investigated whether the protective effects of Neonauclea reticulata water extract against ultraviolet B (UVB) irradiation in human skin fibroblast cell cultures (Hs68) are governed by its ability to protect against oxidative stress and expression of matrix metalloproteinases (MMPs). We found that Neonauclea reticulata extract exhibited DPPH scavenging activity and inhibited A...

Journal: :Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011
Maria J Valente Ana F Baltazar Rui Henrique Letícia Estevinho Márcia Carvalho

This study reports for the first time the biological properties of Portuguese propolis. The antioxidant potential of propolis samples from Bornes (Northeast) and Fundão (Centre) regions of Portugal was evaluated by their ability to inhibit the 2,2'-azobis(2-amidinopropane) dihydrochloride (AAPH)-induced oxidative hemolysis and lipid peroxidation in human erythrocytes. Bornes and Fundão propolis...

Journal: :Metabolism: clinical and experimental 2004
Shiro Mawatari Kazuyuki Saito Kaori Murakami Takehiko Fujino

Correlation of glycated hemoglobin (HbA(1c)) level with degrees of certain peroxidative changes in erythrocyte membrane lipids in diabetic patients have been reported. In the present study, peroxidation of erythrocyte lipids was assessed by changes in tocopherols (Toc), phospholipids (PL), and malondialdehyde (MDA). Membrane cholesterol, Toc, and PL were determined from the same lipid extract. ...

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