selective serotonin reuptake inhibitors (ssris) are reported to be associated with increased bleeding tendency. while findings of recent studies explain a lot about the pathophysiology of this side-effect, there is a general tendency to discontinue ssris as harmful medications. we report two instances of dose-dependent relations between sertraline and bleeding tendency. bleeding diathesis was a...

background: although catalytic properties of different genetic polymorphisms of vkorc1 and cyp2c9 products have been identified, there is limited study available regarding warfarin dose requirement in iranian patient population. this study investigates the impact of these polymorphisms on 115 patients, referred to payvand clinical and specialty laboratory for determining the appropriate dose of...

to improve the accuracy of the activity quantification and the image quality in scintigraphy, scatter correction is a vital procedure. the aim of this study is to compare the accuracy in calculation of absorbed dose to patients following bone scan with 99m tc-marked diphosphonates ( 99m tc-mdp) by two different methods of background correction in conjugate view method. this study involved 22 pa...

background: pregnant women are sometimes exposed to ionizing radiation in radiology examinations for various reasons. in such cases, the radiation dose to the conceptus and subsequent risks should be estimated. objective: the purpose of this study was the calculation and presentation of fetal dose and subsequent risks resulted from different x-ray examinations. materials and methods: an analyti...

Introduction: The CT Provide high quality images, especially in low-contrast soft tissue, are another advantage. Along with all the benefits that the CT scans which have, the patient dose of this modality is much greater than other methods. As a result, medical imaging community must ensure that the benefits of radiological examination for each patient are higher than related r...

Background: Changes in body composition may be used for monitoring progression/ regression of a disease. Prompt γ-rays in vivo neutron activation analysis (IVNAA) has been widely used for the measurement of body composition in recent years.Objective: In this paper, we tried to improve the safety of IVNAA operator.Methods: The most important factor for reducing the operator receiving dose is th...

Twenty patients with torticollis had electromyographic studies of their neck muscles performed before and after a series of local injections of botulinum toxin. The pattern of muscle activity changed after the injections, and this effect persisted even after head position had returned to baseline. Patients who did not experience any clinical benefit from the injections also demonstrated a chang...

intensive induction therapy-in acute myeloid leukemia (aml), as in some other systemic malignancies- is a strategy fundamentally different from post-remission strategies. approaches like consolidation treatment, prolonged mainte nance, and autologous or allogeneic transplantation in the first remission are directed against minimal residual disease with a malignant cell population having survive...