Vitamin A 129 dubious but in practice the results are very good-partly in fact because errors tend to be compensated ! Correction procedures devised specially to meet difficulties over vitamin A assays are actually theoretically safer in most of the many other situations in which they have been used ! I suppose there are lessons here as well as an element of irony. The problem of the site and m...

How the immune system adapts to malnutrition to sustain immunity at barrier surfaces, such as the intestine, remains unclear. Vitamin A deficiency is one of the most common micronutrient deficiencies and is associated with profound defects in adaptive immunity. Here, we found that type 3 innate lymphoid cells (ILC3s) are severely diminished in vitamin A-deficient settings, which results in comp...

We present a case of a vitamin A deficient woman who, presented to our clinic with secondary infertility to emphasize the importance of a good history and a multidisciplinary input in the management. This is a rare case of established vitamin A deficiency related to secondary infertility. Secondary infertility was quickly solved (30-45 days) after restoration of Vitamin A levels and the woman m...

BACKGROUND The reasons for patients to change their usual vitamin K antagonist (VKA) treatment to a direct oral anticoagulant (DOAC) are unexplored. METHOD A random sample of 200 patients treated with VKAs for the indication of atrial fibrillation from the Thrombosis Service in Amsterdam was selected. A survey, using the treatment trade-off technique, was sent to participants. The trade-off i...

Prothrombin is determined with the aid of a recently developed assay, based on the amidolysis of a chromogenic substrate. The assay proved to be reliable when it was compared with more conventional coagulation assays in the control of oral anticoagulant therapy, both in the therapeutic range and in a case of overdosage. As is the case in coagulation tests, heparin therapy remains a disturbing c...

BACKGROUND The use of dietary supplements is widespread and can contribute substantially to total nutrient intake. However, it also generates some potential risks in the case of unreasonable and excessive use of such products. OBJECTIVE To estimate the prevalence of supplementation and the vitamin supplement contribution to total intake among Warsaw population aged 20-74 years. MATERIAL AND...

KERATOCONUS is comparatively speaking a rare disease, but as a clinical entity it has been known for many years. Its aetiology is, however, still obscure, and its treatment is unfortunately one of the failures of ophthalmology. It has been thought that it might be a deficiency disease, and recent attempts to cure the condition by administration of vitamin D and calcium have been made. (Knapp, 1...

The aim of this study was to evaluate the effect of vitamin D supplementation in women with hypovitaminosis D and "small burden" uterine fibroids.This study focused on 208 women diagnosed with uterine fibroids and concomitant hypovitaminosis D, from January to December 2014. One hundred eight women of the initial study population were diagnosed with "small burden" uterine fibroids. Among them, ...

conclusions the vitamin d levels of children aged more than 2 years are lower than those of children aged less than 2 years. thus, prescribing vitamin d-containing supplements in children older than 2 years may be beneficial. results the final study consisted of 286 children, 140 males and 146 females, with a mean age of 4.46 ± 2.82 yr. of these, 218 (76.22%) children, with a mean age of 5.09 ±...