Background: Based on the reports, Aloe vera extract, a herbal medicine, has antimicrobial and anti-inflammatory effects. Also, this medicinal plant has considerable effects on innate immunity through cytokine secretion which resist fungal infections such as Candida albicans. Moreover, Aloe vera is considered as immunomodulatory agent and regulate inflammatory responses. Materials and Methods: I...

conclusions the results suggest that fge can improve the antibiotic sensitivity of these pathogens to some antibiotics. results fresh garlic extract displayed evident inhibition properties against c. albicans and mrsa, yet weak inhibition properties against p. aeruginosa. additionally, fge showed the potential to improve the effect of antibiotics on antibiotic resistant pathogens. the synergism...

conclusions the results suggested that apr1 gene expression in c. albicans strains isolated from ms patients may be an important factor for invasive c. albicans strains in the progression of ms disease. results there was a statistically significant difference in apr1 gene expression of c. albicans strains between ms patients (mean ± sd: 0.5208 ± 0.11518) and the control group (mean ± sd: 0.7603...

Nigrospora oryzae an endophytic fungus isolated from the leaf of a climber Pterolobium hexapetalum (Roth.) Sant. and Wagh. produced bioactive compound which are active against human pathogens. The organic extract (ethanol) of the endophyte Nigrospora oryzae was separated using HPLC and tested for biological activities. The ethanol extract was tested for antibacterial and anti fungal activity us...

Dendritic cells (DCs) are the bridge between the innate and adaptive immune system. DCs are responsible for sensing and patrolling the environment, initiating a host response and instructing the proper adaptive immune response against pathogens. Recent advances in medical treatments have led to increased use of immunosuppressive drugs, leading to the emergence of fungal species that cause life-...

the aim of this study was to investigate the immunomodulatory effects of spirulina platensis (s.platensis) by measuring the levels of serum interleukin (il)-4, il-10, il-17, tumor necrosis factor(tnf)-α and interferon (ifn)-|γ| in mice suffered from systemic candidiasis and breast cancer. theaqueous extract of s. platensis was selected for this study. balb/c female mice were inoculated withcand...

Background: Nanoparticles (NPs) are colloidal systems with particles ranging from 10 to 100 nm in diameter. Because of their large surface-volume ratio, NPs are biologically active materials that could interact with biomolecules and microorganisms, enter into the cells, and affect the metabolic functions. The study aimed to biosynthesize silver nanoparticles (Ag-NPs) from Capparis spinosa fruit...

There is a clear need for the development of a rapid and reliable test for the identification of Candida dubliniensis and for the discrimination of this species from Candida albicans. In the present study we have investigated the potential use of C. dubliniensis-specific antigens as a basis for its identification. We produced an anti-C. dubliniensis serum which, after adsorption with C. albican...

Leaf extract of 12 medicinal plants were obtained by using 10mM sodium phosphate buffer and studied for their antibacterial activity against 6 cariogenic pathogens. Among them, the extract from Streblus asper showed the most intensive activity. Antibacterial activity of Streblus asper was investigated by the minimum inhibitory concentration (MIC) test and the viable cell count method. MIC of St...

Pradimicins A, B and C specify novel antibiotics produced by Actinomadura hibisca No. P157-2 (ATCC 53557) possessing potent and broad antifungal activity in vivo. They showed moderate in vitro antifungal activity against a wide variety of fungi and yeasts including clinically important pathogens, and were highly effective in systemic infection with Candida albicans in mice after iv and im admin...