Objective: The development of new radiopharmaceuticals capable specifically imaging cancer is an important research area. For this reason, the aim study to investigate cell binding novel developed nanoradiopharmaceutical ([99mTc]Tc-nab-PTX) on HT-29 line (human colorectal adenocarcinoma cells).
 Material and Method: In study, nab-PTX was labeled with [99mTc]Tc, labeling efficiency in vitro...

UNLABELLED White blood cell scanning with (99m)Tc-hexamethylpropylene amine oxime (HMPAO) has proven highly sensitive and specific in the diagnosis and follow-up of patients with suspected osteomyelitis. The aim of this prospective study was to evaluate the usefulness of SPECT and transmission CT performed simultaneously using a hybrid imaging device for the functional anatomic mapping of bone ...

BACKGROUND The injection of stem cells in the context of acute myocardial infarction (AMI) has been tested almost exclusively by anterograde intra-arterial coronary (IAC) delivery. The retrograde intravenous coronary (IVC) delivery may be an additional route. OBJECTIVE To compare the cell distribution and retention pattern in the anterograde and retrograde routes. To investigate the role of m...

Electrical and optogenetic methods for brain stimulation are widely used in rodents for manipulating behavior and analyzing functional connectivities in neuronal circuits. High-resolution in vivo imaging of the global, brain-wide, activation patterns induced by these stimulations has remained challenging, in particular in awake behaving mice. We here mapped brain activation patterns in awake, i...

Left hemiparesis exhibited during the post-eruptive stage of exanthem subitum (ES) in an 11-month-old girl. Tc-99m HMPAO brain SPECT showed diffuse hypoperfusion in right hemisphere. Hemiparesis has occasionally been reported as central nervous system (CNS) complications of ES, and Tc-99m HMPAO brain SPECT was useful for evaluating of CNS involvement.

OBJECTIVE The pathogenesis of neurologic and neuropsychologic dysfunction in HIV-1 infection is unclear. The purpose of the study was to determine an association between cerebral perfusion and HIV-1-related ocular microangiopathic syndrome. METHODS We studied 28 HIV-1-infected patients, seven of whom presented with asymptomatic HIV infection, nine with lymphadenopathy syndrome or AIDS-related...