BACKGROUND Environmental tobacco smoke (ETS)-associated particulate matter (PM) has to be seen as an independent health hazard and needs to be discussed separately from the already well-known toxic and carcinogenic compounds contained in cigarette smoke. We believe that brand-specific amounts of PM are of public interest and should be investigated. METHODS An automatic environmental tobacco s...

The kinetics of the reduction of horseheart ferricytochrome c by sodium dithionite (phosphate buffer-sodium chloride; pH 6.5, mu = 1.0, 25 degrees ) features two reaction pathways; one with the rate constant k(3) = 1.17 x 10(4) M(-1) sec(-1), the other with the rate constant k(1)k(2)/k(-1) = 6.0 x 10(4) M(-1) sec(-1). These pathways are interpreted in terms of remote attack (possibly by way of ...

Adenosine diphosphate (ADP) induced aggregation of rabbit platelets, without the release reaction, causes a significant decrease (7%) in the amount of phosphatidylinositol-4,5-bisphosphate (PIP2) at 10 sec and at 60 sec (11%). In platelets prelabeled with 32P-phosphate, this decrease in PIP2 is associated with a decrease in PIP2 radioactivity, which is significant at 50 sec. The decrease in PIP...

This study investigated the effect of different repetition durations on ratings of perceived exertion (RPE) in active muscles (RPE-AM) and the overall body (RPE-O). 19 male volunteers (M age = 25.4 yr., SD = 3.5) performed strength training protocols with multiple sets matched by the number of sets and repetitions, intensity and rest interval but different repetition durations: 4 sec., 6 sec., ...

Neurobehavioral and neurophysiological actions of the peptide endothelin-1 (ET-1) were investigated after subcutaneous plantar hindpaw injections in adult male Sprague Dawley rats. Hindpaw flinching developed within minutes after ET-1 (8-16 nmol) injection, peaked at 30 min, lasted for 60 min, and was strongly inhibited by the endothelin-A (ET(A)) receptor antagonist, BQ-123 (3.2 m). In separat...

Background: IL17 inhibitors (IL17i) are an alternative for patients with axial spondyloarthritis (axSpA) who did not respond to TNF (TNFi). Secukinumab (SEC) is the first human monoclonal antibody that binds protein interleukin-17A. Objectives: The objectives of this study were describe characteristics axSpA treated IL17i and TNFi assess persistence in a real world cohort. Methods: A retrospect...

The main objective of this work is to develop a mathematical model to evaluate optimum sanding conditions of Europen black pine (Pinus nigra). Samples were sanded using different of grit size, feed rate, cutting speed and depth of cut. Average surface roughness (Ra) values of each type of specimens were measured employing a stylus type of equipment. Interaction between sanding parameters and su...

This study investigated the relationships among exercise capacity (EC), dynamic balance (DB), and gait characteristics (GCs) of patients with type-2 diabetes (T2D) and healthy controls (HCs). This observational controlled study involved 125 patients with T2D receiving treatment at a Nigerian university teaching hospital and 125 apparently healthy patients' relatives and hospital staff recruited...

[1] Aerosol samples were collected in Zurich, Switzerland, at an urban background site and were analyzed with size exclusion chromatography (SEC) and laser/desorption ionization mass spectrometry (LDI-MS) for water-soluble organic compounds with high molecular weight. Daily samples were collected during two campaigns in winter and summer, for 1 month each. The concentration of high-molecular-we...