نتایج جستجو برای: 786c polymorphism

تعداد نتایج: 107362  

Journal: :archives of clinical infectious diseases 0
maliheh metanat infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran mehrnaz narooie nejad genetic of non-communicable disease research center, zahedan university of medical sciences, zahedan, ir iran; genetic of non communicable disease research center, zahedan university of medical sciences, zahedan, ir iran. tel: +98-541 3228101-2, fax: +98-5413229792 masoud salehi infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran javad moazen infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran esmail sanei-moghaddam blood transfusion organization, zahedan, ir iran narges arbabi infectious diseases and tropical medicine research center, zahedan university of medical sciences, zahedan, ir iran

background almost one-third of the world's population is infected with mycobacterium tuberculosis, but only 10% of them develop tuberculosis. tnf-α/il-10 balance has key roles in controlling latent/activation stages of tuberculosis. objectives the objective of this study was to determine an association between polymorphic variants of the tnf-α and il-10 genes and tuberculosis. patients and meth...

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Journal: :hepatitis monthly 0
mohammad hashemi cellular and molecular research center, zahedan university of medical sciences, zahedan, ir iran; department of clinical biochemistry, school of medicine, zahedan university of medical sciences, zahedan, ir iran; department of clinical biochemistry, school of medicine, zahedan university of medical sciences, zahedan, ir iran. tel: +98-9173640366, fax: +98-5413414571 hamideh hanafi bojd department of clinical biochemistry, school of medicine, zahedan university of medical sciences, zahedan, ir iran ebrahim eskandari nasab department of clinical biochemistry, school of medicine, zahedan university of medical sciences, zahedan, ir iran ali bahari department of internal medicine, school of medicine, mashhad university of medical sciences, mashhad, ir iran noor allah hashemzehi department of internal medicine, school of medicine, zahedan university of medical sciences, zahedan, ir iran sara shafieipour department of internal medicine, school of medicine, kerman university of medical sciences, kerman, ir iran

patients and methods eighty-three patients with diagnosis of nafld, and 93 healthy subjects were included in the study. tetra arms-pcr was designed to detect single nucleotide polymorphisms. results a significant difference was found between nafld and control group regarding the rs266729 polymorphism (χ2 = 7.35, p = 0.025). the rs266729 polymorphism increased the risk of nafld in codominant (cc...

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Journal: :journal of sciences, islamic republic of iran 2012
m. mohaddes

type 2 diabetes mellitus (t2d) is the most common metabolic disease demonstrating itself by hyper- glycemia, due to impaired insulin secretion or action. recently, whole-genome association studies have revealed the role of several new genes responsible for t2d. one of the most studied genes is slc30a8 (zn-t8) which is exclusively expressed in pancreatic ?-cells and participates in insulin stora...

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Journal: :Asian Pacific Journal of Cancer Prevention 2015

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2011
Yoji Suyama Chikashi Matsuda Minoru Isomura Tsuyoshi Hamano Kenji Karino Masayuki Yamasaki Shuhei Yamaguchi Kuninori Shiwaku Junichi Masuda Toru Nabika

Oxidative stress is an important risk factor for cardiovascular diseases. Although a variety of genetic factors are assumed to contribute to the regulation of oxidative stress, evidence in human populations is insufficient. In this study, we therefore evaluated the effects of six functional single-nucleotide polymorphisms (SNPs) on the oxidative stress under a cross-sectional study design. Part...

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ژورنال: مجله پزشکی ارومیه 2015
شرف بیانی, مرضیه, گودرزی , محمدتقی, برزوئی, شیوا , سعیدی جم , مسعود , سلطانیان , علیرضا , محمدیان,  مهشید , کریمی, جمشید ,

   Background & aims: Metabolic Syndrome (MetS) is a potential threatening factor for cardiovascular disorders and atherosclerosis which is accompanied by increase in plasma triglyceride, cholesterol, low density lipoproteins (LDL-c), fasting blood sugar (FBS) and low high density lipoproteins (HDL-c). Cholesteryl ester transfer protein (CETP) catalysis transfer of lipids and phospholipids betw...

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Journal: :acta medica iranica 0
navid nilforoushan department of ophthalmology, eye research center of rasoul hospital, tehran university of medical sciences, tehran, iran. sevil aghapour department of ophthalmology, eye research center of rasoul hospital, tehran university of medical sciences, tehran, iran. and department of medical genetics, tehran university of medical sciences, tehran, iran. reza raoofian department of medical genetics, tehran university of medical sciences, tehran, iran. samira saee rad department of medical genetics, tehran university of medical sciences, tehran, iran. wayne k. greene school of veterinary and biomedical sciences, faculty of health sciences, murdoch university, perth wa 6150, australia. ghasem fakhraie eye research center, farabi eye hospital, tehran university of medical sciences, tehran, iran.

glaucoma is a major cause of blindness worldwide. a single nucleotide polymorphism of the mthfr gene (c677t) has been associated with susceptibility to this disease, although this is controversial in the last decade. in this study, the possible association between the mthfr c677t polymorphism and the risk of developing primary open angle (poag) and pseudoexfoliation glaucoma (pexg) was investig...

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Journal: Journal of Kerman University of Medical Sciences 2017
Mahdieh Younesi Mohammadali HosseinpourFeizi, Nasser Pouladi

Background: Due to the lack of information about the role of 4G/5G polymorphism of PAI-1 Gene in susceptibility to thyroid tumors, this study was performed to evaluate the potential effects of this polymorphism on clinicopathologic features of thyroid tumors in Iranian Azeri Turkish patients. Methods:In this case-control study, 90 patients with thyroid tumors ...

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Journal: مجله بین المللی علوم آزمایشگاهی 2016
Ehsan Farashahi, Mohammad Ataei, Morteza Seifati, Nasrin Ghasemi,

Background and Aims: This research aimed to study a possible link between endometriosis and polymorphism of the progesterone receptor gene. Materials and Methods: The control group consisted of 86 women without endometriosis and the case group comprised 86 patients with a diagnosis of endometriosis by laparoscopy. Genotypes for Alu insertion polymorphisms (A1/A1, A1/A2 and A2/A2) were descri...

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ژورنال: مجله دانشگاه علوم پزشکی مازندران 2013
آهنگر , نعمت الله, کشاورز, راضیه ,

Background and purpose: The human multidrug resistance gene (MDR1) encodes for P-glycoprotein (P-gp) which is a transmembrane transporter protein acts as an efflux pump for a number of xenobiotics. It plays a protective role for cells against DNA damage caused by toxins and drugs. The wobble C3435T polymorphism at exon 26 has been associated with different expression levels and activities of th...

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