نتایج جستجو برای: 73649 ha

تعداد نتایج: 59532  

Journal: :Anales del Instituto de Investigaciones Estéticas 1968

Journal: :Journal of immunology 2002
Bregje Mommaas Janine Kamp Jan-Wouter Drijfhout Nico Beekman Ferry Ossendorp Peter Van Veelen Joke Den Haan Els Goulmy Tuna Mutis

The polymorphic minor histocompatibility Ag HA-1 locus encodes two peptides, HA-1(H) and HA-1(R), with a single amino acid difference. Whereas the immunogenicity of the HA-1(R) allele has not yet been shown, the nonameric HA-1(H) peptide induces HLA-A2-restricted cytotoxic T cells in vivo and in vitro. It is not known whether the mHag HA-1(H) or HA-1(R) associates with other HLA class I molecul...

Journal: :Revista Repertorio de Medicina y Cirugía 2001

Journal: :Tidsskrift for Den norske legeforening 2021

Journal: :Tidsskrift for Den norske legeforening 2013

Journal: :Matrix biology : journal of the International Society for Matrix Biology 2009
Hélène Lenormand Frédéric Tranchepain Brigitte Deschrevel Jean-Claude Vincent

Hyaluronan (HA) hydrolysis catalysed by hyaluronidase (HAase) is strongly inhibited when performed at low HAase over HA concentration ratio and under low ionic strength conditions. The reason is the ability of long HA chains to form electrostatic and non-catalytic complexes with HAase. For a given HA concentration, low HAase concentrations lead to very low hydrolysis rates because all the HAase...

2017
Seong Uk Son Jae-Woo Lim Taejoon Kang Juyeon Jung Eun-Kyung Lim

We suggest a convenient nanoemulsion fabrication method to create hyaluronan (HA)-based nanohydrogels for effective transdermal delivery. First, hyaluronan-conjugated dodecylamine (HA-Do) HA-based polymers to load the lipophilic agents were synthesized with hyaluronan (HA) and dodecylamine (Do) by varying the substitution ratio of Do to HA. The synthetic yield of HA-Do was more than 80% (HA-Do ...

2017
Hiba Ahmad Zahreddine Biljana Culjkovic-Kraljacic Audrey Emond Filippa Pettersson Ronald Midura Mark Lauer Sonia Del Rincon Valbona Cali Sarit Assouline Wilson H Miller Vincent Hascall Katherine Lb Borden

The microenvironment provides a functional substratum supporting tumour growth. Hyaluronan (HA) is a major component of this structure. While the role of HA in malignancy is well-defined, the mechanisms driving its biosynthesis in cancer are poorly understood. We show that the eukaryotic translation initiation factor eIF4E, an oncoprotein, drives HA biosynthesis. eIF4E stimulates production of ...

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