(FRS, correspondence: [email protected]) General Editor, P.O. Box 1569, Langley, Washington 98260, U.S.A.; (STA) P.O. Box 14-901, Kilbirnie, Wellington, New Zealand; (KAC) Department of Integrative Biology, Brigham Young University, Provo, Utah 84602-5181, U.S.A.; (FG) Biologia Animale e Genetica, Università degli Studi di Firenze, Via Romana 17, I-50125, Firenze, Italy; (MJG) Lake Biwa Museum, O...

A novel gland segmentation and classification scheme applied to an H&E histology image of the prostate tissue is proposed. For gland segmentation, we associate appropriate nuclei objects with each lumen object to create a gland segment. We further extract 22 features to describe the structural information and contextual information for each segment. These features are used to classify a gland s...

The objective of the study was to identify the profile of circulating C19MC microRNAs (miR-516-5p, miR-517*, miR-518b, miR-520a*, miR-520h, miR-525, and miR-526a) in patients with established preeclampsia (n = 63), fetal growth restriction (n = 27), and gestational hypertension (n = 23). We examined the correlation between plasmatic concentrations and expression levels of microRNAs and the seve...

Tandutinib (MLN518/CT53518) is a novel quinazoline-based inhibitor of the type III receptor tyrosine kinases: FMS-like tyrosine kinase 3 (FLT3), platelet-derived growth factor receptor (PDGFR), and KIT. Because of the correlation between FLT3 internal tandem duplication (ITD) mutations and poor prognosis in acute myelogenous leukemia (AML), we conducted a phase 1 trial of tandutinib in 40 patie...

Recipient age at transfer (less than 525 d old or more than 525 d old), season (fail, winter, spring, summer), method of synchronization (natural or induced), and transfer technique (surgical or nonsurgical transfer) were associated with success of embryo transfer in a log-linear analysis. In a separate analysis, no significant association was found between success of transfer and transfer to t...

Measles virus is a negative-sense, single-stranded RNA virus within the Mononegavirales order,which includes several human pathogens, including rabies, Ebola, Nipah, and Hendra viruses. The measles virus nucleoprotein consists of a structured N-terminal domain, and of an intrinsically disordered C-terminal domain, N(TAIL) (aa 401-525), which undergoes induced folding in the presence of the C-te...

We designed a novel aptamer based biosensor (aptasensor) for ultrasensitive detection of adenosine triphosphate (ATP) through resonance energy transfer (RET). The ATP aptamer was modified with Cy3 at the 3' end, and a green quantum dot (525) was attached to the 5' end of its complementary sequence respectively. The ATP aptamer and its complementary sequence could assemble into a duplex structur...

I G. Kallianpur and H. Robbins, "Ergodic Property of the Brownian Motion Process," these PROCEEDINGS, 39, 525-533, 1953, and "The Sequence of Sums of Independent Random Variables," I)uke Alath. J. 21, 285-308, 1954. 2 H. Robbins, "On the Equidistribution of Sums of Independent Random Variables," Proc. Aml. Math. Soc., 4, 786-799, 1953. 3 T. E. Harris and H. Robbins, "Ergodic Theory of Markov Ch...

Resistance exercise load does not determine training-mediated hypertrophic gains in young men 1 Cameron J. Mitchell, Tyler A. Churchward-Venne, Daniel D.W. West, Nicholas A. Burd, Leigh 2 Breen, Steven K. Baker, Stuart M. Phillips 3 Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, Hamilton, 4 ON, Canada 5 Department of Neurology and Medicine, McMaster Universi...

E quantile sensitivities is important in many optimization applications, from hedging in financial engineering to service-level constraints in inventory control to more general chance constraints in stochastic programming. Recently, Hong (Hong, L. J. 2009. Estimating quantile sensitivities. Oper. Res. 57 118–130) derived a batched infinitesimal perturbation analysis estimator for quantile sensi...