granymeh is a functional cytotoxic serine protease of nk cell granules,which expands the cell death-inducing repertoire of innate immune system.the purpose of this study was to determine granymeh(gzmh)level in breast cancer(bc) and healty women.this study was performed on 30 patients with bc and 30 healty woman.gzmh and estrogen levels were measured in cancer patients  and healty women subseque...

Measurements of black carbon (BC) concentration have long been uncertain. Neither a BC standard or a technique that provides a reliable measurement of BC exist, which precludes the evaluation and optimization of BC measurement methods. In this manuscript, we describe the generation of BC particles (mass absorption efficiency 8.5m g 1 and single scattering albedo 0.2 at 530 nm) using an inverted...

Optically transparent membranes from bacterial cellulose (BC)/polycaprolactone (PCL) have been prepared by impregnation of PCL acetone solution into dried BC membranes. UV-Vis measurements showed an increase on transparency in BC/PCL membrane when compared with pristine BC. The good transparency of the BC/PCL can be related to the presence of BC nanofibers associated with deposit of PCL nano-si...

The biological activity of two novel 14-epi-analogues of 1,25(OH)2D3, 19-nor-14-epi-23-yne-1,25(OH)2D3 (TX 522) and 19-nor-14,20-bisepi-23-yne-1,25(OH)2D3 (TX 527), is described. Both analogues were at least 10 times more potent than 1,25(OH)2D3 in inhibiting in vitro cell proliferation and had much lower in vivo calcemic effects than 1,25(OH)2D3. Treatment with 1,25(OH)2D3, TX 522, or TX 527 i...

Squalamine, an antiangiogenic aminosterol, is presently undergoing Phase II clinical trials in cancer patients. To broaden our understanding of the clinical potential for squalamine, this agent was evaluated in nu/nu mouse xenograft models using the chemoresistant MV-522 human non-small cell lung carcinoma and the SD human neuroblastoma lines. Squalamine was studied alone and in combination wit...

Vanessa Wiggermann, Lisa E. Lee, Enedino Hernández Torres, David K.B. Li, Alex L. MacKay, Irene M. Vavasour, Anthony Traboulsee, and Alexander Rauscher Radiology, University of British Columbia, Vancouver, BC, Canada, Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, Science, University of British Columbia, Vancouver, BC, Canada, UBC MRI Research Centre, Vancouver, B...

P. Kozlowski, S. D. Chang, E. C. Jones, R. Meng, N. Buchan, and S. L. Goldenberg UBC MRI Research Centre, Vancouver, BC, Canada, Radiology, Univeristy of British Columbia, Vancouver, BC, Canada, Pathology and Laboratory Medicine, Univeristy of British Columbia, Vancouver, BC, Canada, Vancouver Prostate Centre, Vancouver, BC, Canada, Urologic Sciences, Univeristy of British Columbia, Vancouver, ...

Pattern / Normalization Resources •1–4 digit years • “BC/AD” phrases Rules •several modifications and new rules • rules with explicit “BC/AD” phrases • rules without “BC/AD” phrases Normalization Strategies •calculations for relative and underspecified expressions •disambiguation of 2-digit years •expressions without “BC/AD” phrases ∗preliminary normalized to AD dates ∗ if explicit BC dates in ...

The sectoral and regional contributions from northern hemisphere anthropogenic and biomass burning emission sectors to black carbon (BC) distributions over the continental United States (CONUS) in summer 2008 are studied using the Sulfur Transport and dEposition Model (STEM). North American (NA) emissions heavily (>70% of total emissions) affect the BC levels from the surface tow5 km, while non...

Two high-performance bacterial cellulose (BC) nanofiber-based hybrid structures were produced using an in situ self-assembly approach, one with microfibrillated cellulose (MFC) and another with sisal fiber, by incorporating them in the fermentation media. The fabricated BC-MFC hybrid and BC-sisal hybrid fibers showed enhanced mechanical properties compared to pure BC and sisal fibers, respectiv...