The development of cerebral malaria (CM) in mice with Plasmodium berghei ANKA infection is under genetic control. Brain gene-expression patterns were investigated in well-defined genetically CM-resistant (CM-R; BALB/c and DBA/2) and CM-susceptible (CM-S; C57BL/6 and CBA/J) mice by use of cDNA microarrays. By combining transcriptional profiling with rigorous statistical methods and cluster analy...

We describe the implementation of a fluid dynamical benchmark on two Thinking Machines Corporation parallel computers the 65,536 processor CM-200 computer and the 1024-node CM-5 computer. The benchmark, the Shallow Water Equations, is frequently used as a model for both oceanographic and atmospheric circulation. We describe the steps involved in implementing the algorithm on the computers and w...

Among the samples received in pathology laboratory, Pakistan Institute of Medical Sciences, Islamabad, 5069 samples had bacterial growth, among these 2580 (51%) samples were Gram-positive cocci and 1688 were Staphylococcus aureus during a period of two years. Out of these Gram-positive cocci 56% were resistant to penicillin group, 27% were resistant to cephalosporin group, 22% were resistant to...

OBJECTIVE To investigate the etiology of deafness in cochlear implanted children and to address the question whether there is a need for more thorough diagnostics, especially concerning genetics. DESIGN Systematic review. Four databases were searched for studies (year 2000-2014) on cochlear implanted children (n > 100). Studies were excluded if etiology had influenced their inclusion criteria...

PURPOSE Determining the ideal length of a ureteric stent is important to avoid complications associated with stent placement. Clinically, most urologists usually choose the length of a ureteric stent according to the patient's height. On the basis of a Chinese population study, a 22 cm ureteric stent has been recommended for patients smaller than 175 cm. We evaluated the appropriateness of this...

The Connection Machine CM-5 supports both SIMD and MIMD programming modes. The SIMD mode is simulated over the MIMD mode. This simulation is likely to lead to a loss of performance in SIMD programs. This paper describes the design and implementation of benchmarks which were used to bring out the diierence in speed between the two programming modes with CM Fortran and message-passing Fortran. Tw...

A detector for high-resolution momentum measurements of neutrons in the energy range 0.2-1.0 GeV is being developed for the RB experiment at FAIR. Two solutions are currently being studied: A pure scintillator concept and an approach based on a sequence of converter material (iron) to produce secondary charged particles, and Multigap Resistive Plate Chambers (MRPC’s) to detect these particles. ...

We present new high-resolution observations of Sagittarius A* at wavelengths of 17.4 to 23.8 cm with the Very Large Array in A configuration with the Pie Town Very Long Baseline Array antenna. We use the measured sizes to calibrate the interstellar scattering law and find that the major axis size of the scattering law is smaller by ∼ 6% than previous estimates. Using the new scattering law, we ...

Recently, many details of the interplay between tumor cells and tumor-associated stromal elements leading to the progression of malignant disease were elucidated. In contrast, little is known about the role of uninvolved stromal tissue in the remote surrounding of the malignant tumor. Therefore, we performed a computer-aided morphometric study of rectal mucosa in samples taken 10 cm and 20 cm a...

Diagnosing UTIs is done through a combination of clinical history, examination, and laboratory tests. Infants and the elderly may present with no symptoms at all. Other patients might complain of fever, chills, anorexia, nausea, vomiting, diarrhea, pain in the abdomen or back, dysuria, hematuria, incontinence, decreased urine output or the inability to urinate, and/or altered mental status/conf...