The most important antiscorbutic foods are now known to be the fruits and vegetables, and it is usually considered that these foods are chiefly, if not onIy, vahrable for this property when used fresh. Holst and E’riihlich (1) showed that cooking and canning or drying greatly decreased the antiscorbutic value of a variety of foods. Since the danger of scurvy is greatest under those circumstance...

Hormones and sensory stimuli activate serpentine receptors, transmembrane switches that relay signals to heterotrimeric guanine nucleotide-binding proteins (G proteins). To understand the switch mechanism, we subjected 93 amino acids in transmembrane helices III, V, VI, and VII of the human chemoattractant C5a receptor to random saturation mutagenesis. A yeast selection identified 121 functioni...

I argue that proper assertion requires belief. Jennifer Lackey has recently argued otherwise. Here I respond to Lackey’s argument and provide positive evidence that permissible assertion does require belief. The positive evidence takes the form of an explanatory argument from linguistic patterns surrounding the give and take of assertion. Looming large in the background of the discussion is whe...

The ability of generating and interpreting a threedimensional representation of the environment in real-time is one of the key technologies for autonomous vehicles. While active sensors like ultrasounds have been commercially used, their cost and precision is not favorable. On the other hand, integrating passive sensors, like video cameras, in modern vehicles is quite appealing especially becau...

In previous studies we have reported that a) marked sensitivity to leucine hypoglycemia can be induced consistently in healthy subjects after the oral administration of sulfonylureas, compounds that are known to stimulate islet cell activity (1), b) a modest but significant hypoglycemic effect can be produced by administering leucine to healthy subjects without sulfonylurea pretreatment (1, 2),...

Current epistemological orthodoxy has it that knowledge is incompatible with luck. More precisely: Knowledge is incompatible with epistemic luck (of a certain, interesting kind). This is often treated as a truism which is not even in need of argumentative support. In this paper, I argue that there is lucky knowledge. In the first part, I use an intuitive and not very developed notion of luck to...

1. Y. Baba, On maxima of Takagi–van der Waerden functions, Proc. Amer. Math. Soc. 91 (1984) 373–376. 2. P. Billingsley, Van der Waerden’s continuous nowhere differentiable function, this MONTHLY 89 (1982) 691. 3. A. M. Bruckner, J. B. Bruckner, and B. S. Thomson, Real Analysis, Prentice Hall, Upper Saddle River, NJ, 1997. 4. F. S. Cater, On van der Waerden’s nowhere differentiable function, thi...

In recent years we witness the proliferation of semidefinite programming bounds in combinatorial optimization [1,5,8], quantum computing [9,2,3,6,4] and even in complexity theory [7]. Examples to such bounds include the semidefinite relaxation for the maximal cut problem [5], and the quantum value of multi-prover interactive games [3,4]. The first semidefinite programming bound, which gained fa...

Within only a few years, the use of e-learning has increased rapidly in Austria. In certain subjects, up to 60% of university students report using e-learning platforms at least ‘sometimes’ or ‘frequently’ (Unger & Wroblewski, 2006). Yet, which aspects of e-learning do students consider important for their learning achievements and course satisfaction? This question was addressed by surveying 2...

Engl 7Mcd 1986;314:222-5. 38 Nagulesparan MN1, Savage PJ. Unger R, Bennett PH. A simplified method tising somatostatiii to assess in vivo insulin resistance over a range of' obesitY. Diabetes 1979;28:980-3. 39 Luft R, WX'ajngot A, Efenidic S. On the pathogenesis of maturitv onset diahetes. Diabetes Care 198X ;4:58-63. 41) DeFroiuzo RA. The triumvirate: beta-cell, muscle, liver. A collusion resp...