The mol-ecule of the title compound, C21H17N3O, is built up from fused five- and six-membered rings connected to a methyl group, a phenyl ring and an (imino-meth-yl)phenol group. The fused ring system is almost planar (r.m.s. deviation = 0.031 Å) and forms dihedral angles of 64.97 (7) and 18.52 (6)° with the phenyl ring and the (imino-meth-yl)phenol group, respectively. In the crystal, centrosy...

In this research, an efficient synthesis toward 2-(2-((4-Methoxybenzoyl)imino)-4-(4-methoxyphenyl)thiazol-3(2H)-yl)-2-phenylacetic acid via a three-component tandem reaction using aroylisothiocyanate, phenyl glycine, and 4-methoxyphenacyl bromide in an ionic liquid (IL) has been described. 1-Methyl-3-pentylimidazolium bromide (IL) has been employed as a recyclable green solvent. The work-up pro...

a group of 1,3-biarylhydrazide derivatives possessing a cox-2 azido pharmacophore at the para- position of the c-1 phenyl ring in conjunction with a n-3 phenyl or substituted-phenyl ring (4-f,4-cl,4-ome) were designed and synthesized based on nucleophilic substitution reaction. a molecular modelling study of these compounds showed that the designed molecules were well bound with the active site...

The imino C=N double bond in the title compound, C(14)H(10)N(2)O, exists in an E conformation, with the phenyl ring being twisted by 80.7 (1)° in one independent mol-ecule and by 81.4 (1)° in the other with respect to the plane of the indoline fused-ring system. The two independent mol-ecules are linked by N-H⋯O hydrogen bonds, forming a zigzag chain running along the a axis.

1-(4- Chloro -1-hydroxynaphthalen-2-yl)-ethanone was prepared by refluxing 4-chloronaphthalen-1-ol with glacial acetic acid in presence of fused ZnCl2. From this synthesized compound we -1- hydroxynaphthalen-2-yl)-3-(4-hydroxy phenyl)-prop-2-en-1-one from condensing -1-hydroxynaphthalen-2- yl)-ethenone, The final product 6-(5-chloro-8-hydroxynapthalene-2-yl)-4(4-hydroxyphenyl)-4-5-dihydroxypyri...