INTRODUC~ON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 337 Materialsandmethods . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 338 Percentage mortalities due to varying numbers of bacteria.. . . . . . . . . . . . . . . . . . . . . . . . ....

This poster presents a new 5 GHz combined MERLIN/VLA map of B0218+357 which shows for the first time believable substructure in the Einstein ring. This will now be exploited for further constraints on the model which presently dominates the error on the estimate of H 0 derived from the time delay (10.5±0.4 days) measured for this system.

Role of prostate apoptosis response-4 (PAR-4) has been well described in prostate cancer. However, its significance in other cancers has not been fully elucidated. For the current study, we selected four pancreatic cancer cell lines (BxPC-3, Colo-357, L3.6pl, and HPAC) that showed differential endogenous expression of PAR-4. We found that nonpeptidic small-molecule inhibitors (SMI) of Bcl-2 fam...

Fluconazole is being increasingly used to prevent and treat invasive candidiasis in neonates, yet dosing is largely empirical due to the lack of adequate pharmacokinetic (PK) data. We performed a multicenter population PK study of fluconazole in 23- to 40-week-gestation infants less than 120 days of age. We developed a population PK model using nonlinear mixed effect modeling (NONMEM) with the ...

Truncated glycine receptors that have been found in human patients suffering from the neuromotor disorder hyperekplexia or in spontaneous mouse models resulted in non-functional ion channels. Rescue of function experiments with the lacking protein portion expressed as a separate independent domain demonstrated restoration of glycine receptor functionality in vitro. This construct harbored most ...

Pulsed laser methods for OH generation and detection were used to study atmospheric degradation reactions for three important biogenic gases: OH + isoprene (R1); OH + -pinene (R2); and OH + -3-carene (R3). Gas-phase rate coefficients were characterised by non-Arrhenius kinetics for all three reactions. For (R1), k1(241-356 K) = (1.93  0.08)10 15 exp{(466  12)/T} cmmolecule s was determined...

Nikolas Dimakis, Social identity in the classical and hellenistic northern Peloponnese: evidence from burials. pp. ix + 357, 111 figs (7 col.). Oxford: Archaeopress, 2016. ISBN 978-1-78491-506-3, paperback £40; 978 1 78491 507 0, E-book £16.

Abstract IODP Expedition 357 drilled 17 shallow sites scattered over ~ 10 km in the west to east spreading direction across Atlantis Massif oceanic core complex (OCC, MAR, 30 ºN). Mantle exposed footwall of Atlantic OCC is nearly wholly serpentinized (80–100%) harzburgite and subordinate dunite. A recent whole-rock chemistry study by Whattam et al. (Chemical Geology 594. 10.1016/j.chemgeo.2021....