The mechanistic understanding of interactions between diet-derived substances and conventional medications in humans is nascent. Most investigations have examined cytochrome P450–mediated interactions. Interactions mediated by other phase I enzymes are understudied. Aldehyde oxidase (AO) is a phase I hydroxylase that is gaining recognition in drug design and development programs. Taken together...

Since the establishment of the first point-to-point radio communication by GuglielmoMarconi in 1895, the complexity of communication systems has grown dramatically in the continuing search for higher system capacity, higher data rates, and bandwidth efficiency. Research in information theory and digital signal processing has been the foundation for the development of systems that are able to ha...

با توجه به تغییرات گسترده، مداوم و روزافزون در بازارهای جهانی تقاضای مشتریان، به‌کارگیری ابزارهایی قدرتمند قابل‌اطمینان برای پشتیبانی از تصمیم‌گیرندگان، اجتناب‌ناپذیر است. این منظور پژوهش حاضر، مسئله برنامه‌ریزی تولید شرایط احتمالی یک سیستم تولیدی هیبرید MTS/MTO بررسی شده رویکرد، مدل ارائه‌شده را به‌طور کامل MTO یا MTS نیز سازگار کرده به‌طورمعمول بازه میان‌مدت صورت گرفته است تصمیمات اخذشده هر م...

1Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan. ABSTRACT A longitudinal study was done in a leishmaniasis-endemic region in eastern Sudan during the period November 2001–February 2003 to determine the incidence of failure of sodium stibogluconate treatment. We studied 820 confirmed visceral leishmaniasis patients. All were treated with sodium stibogluconate, 20 mg/kg bo...

ity and on the receipt of infertility services from the 1995 National Survey of Family Growth (NSFG) allow us to determine whether and how these phenomena have changed since they were last measured in 1988. Such trend analysis has implications for projecting future health care costs, particularly in an arena of changing insurance coverage and potential health care reform. It may also be relevan...