Microvillus inclusion disease (MVID) is a life-threatening enteropathy characterised by malabsorption and incapacitating fluid loss due to chronic diarrhoea. Histological analysis has revealed that enterocytes in MVID patients exhibit reduction of microvilli, presence of microvillus inclusion bodies and intestinal villus atrophy, whereas genetic linkage analysis has identified mutations in myos...

Oxidative stress with subsequent production of reactive oxygen species has been postulated as one of the mechanisms of naphthalene toxicity. In the present study, the effect of oral administration of the natural antioxidant and free radical scavenger, proanthocyanidins present in grape seeds (GSP, 10 or 50 mg kg, p.o.), has been investigated in rats following the concomitant administration of n...

A common modeling assumption in the realm of cost sharing is that players persuade each other to jointly submit false bids if none of the members of such a coalition loses utility and at least one gains. In order to counteract this kind of manipulation, the service provider could employ group-strategyproof (GSP) mechanisms that elicit truthful bids. The basically only general technique for the ...

Modern sponsored search auctions are derived from the Generalized Second Price (GSP) auction. Although the GSP auction is not truthful, results by Edelman, Ostrovsky, and Schwarz [7] and Varian [13] give senses in which its outcome is equivalent to that of the truthful and welfaremaximizing VCG mechanism. The first main message of this paper is that these properties are not unique to the GSP au...

Rats lacking chorda tympani nerve (CT) input, a facial nerve branch innervating anterior tongue taste buds, show robust impairments in salt discrimination demonstrating its necessity. Here, we tested the sufficiency of the CT for salt taste discrimination, and whether the remaining input provided by either the greater superficial petrosal nerve (GSP), a facial nerve branch innervating palatal t...

Leukocytes roll on selectins at nearly constant velocities over a wide range of wall shear stresses. Ligand-coupled microspheres roll faster on selectins and detach quickly as wall shear stress is increased. To examine whether the superior performance of leukocytes reflects molecular features of native ligands or cellular properties that favor selectin-mediated rolling, we coupled structurally ...

1. In this note, we shall describe a classification for automorphic representations of GSp(4), the group of similitudes of four-dimensional symplectic space. The results are part of a project [A3] on the automorphic representations of general classical groups. The monograph [A3] is still in preparation. When complete, it will contain a larger classification of representations, subject to a gene...