1 Pediatric Institute (IPPMG), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil. Send correspondence and reprint requests to: Patricia de Carvalho Padilha, Rua Gramado 475, Bloco C, Apto. 202, Campo Grande, CEP 23050-090, Rio de Janeiro, RJ, Brasil; e-mail: [email protected] 2 Maternal and Child Health Research Group (GPSMI), Center for Micronutrient Research (NPq...

Mailing Address: Márcia Maria Carneiro Oliveira • Programa de Pós-Graduação em Medicina e Saúde da Universidade Federal da Bahia. Rua Acajutiba, Quadra 8, Lote 13 B, Pernambués. Postal Code 41120-700, Salvador, BA – Brazil E-mail: [email protected] Manuscript received June 21, 2015; revised manuscript June 26, 2015; accepted July 06, 2015.

1 Speech and Language Pathologist – Doctoral Student at Institute of Education University of Minho – Research Center in Education. Grant Researcher for the Portuguese Foundation for Science and Technology SFRH/BD/70351/2010, Project Co-funded by the European Social Fund. Rua Simões de Almeida no 95 casa 41, 4715 – 105 Portugal – Braga. 2 Ph.D., Associate Professor University of Minho – Institut...

1 Medical Genetics Service, Hospital de Cĺınicas de Porto Alegre, Rua Ramiro Barcelos, 2350, 90035-903 Porto Alegre, RS, Brazil 2 PPG Ciências Farmacêiticas, Universidade Federal do Piauı́, 64049-550 Terezina, PI, Brazil 3 Genetics Service, Hospital Universitário, Universidade Federal de Santa Catarina, 88040-900 Florianópolis, SC, Brazil 4 PPG BioSaúde, Universidade Luterana do Brasil, Avenida ...

We have delimited the extra sex combs (esc) gene to < 4 kb that include a single transcript and are able to rescue both the maternal and zygotic esc phenotypes. Several mutations have been identified within the esc transcript. In agreement with earlier genetic studies, esc is expressed maternally and its product is most abundant during the early embryonic stages. It encodes a protein of the WD-...

Epigenetic mechanisms such as DNA methylation are essential regulators of the function and information storage capacity of neurons. DNA methylation is highly dynamic in the developing and adult brain, and is actively regulated by neuronal activity and behavioural experiences. However, it is presently unclear how methylation status at individual genes is targeted for modification. Here, we repor...

4. Prentice RL, Manson JE, Langer RD, Anderson GL, Pettinger M, Jackson RD, et al. Benefits and risks of postmenopausal hormone therapy when it is initiated soon after menopause. Am J Epidemiol. 2009; 170 (1): 12-23. References Mailing address: Flávio Danni Fuchs • Rua Ramiro Barcelos 2350, Sala 2060 Rio Branco 90035-903 Porto Alegre, RS Brazil E-mail: [email protected] Manuscript received D...

*Departamento de Zoologia e Antropologia da Faculdade de Cie“ ncias da Universidade do Porto, Prac a GomesTeixeira, 4099-002 Porto, Portugal. CIIMAR, Rua dos Bragas 177, 4050-123 Porto, Portugal. Faculdade de Cie“ ncias da Sau¤ de da Universidade Fernando Pessoa, Rua Carlos da Maia 296, 4200-150 Porto, Portugal. ISPA, Rua Jardim doTabaco 34, 1149-041 Lisboa, Portugal. Corresponding author, e-ma...