The comparative efficacy and safety profiles of selected daily 1000 IU, weekly 7000 IU and monthly 30,000 IU vitamin D 3-not previously investigated-will be evaluated. Here, a prospective, randomized clinical trial, comparing efficacy and safety of a daily single dose of 1000 IU (group A) to a once-weekly 7000 IU dose (group B), or monthly 30,000 IU dose (group C) of vitamin D3. The present stu...

OBJECTIVE To investigate the effect of Vitamin D3 on physical performance in patients with HF. BACKGROUND HF is associated with functional decline and frailty. Vitamin D deficiency is associated with loss of muscle strength and poor outcomes in patients with HF. METHODS Sixty-four patients participated in a 6-month parallel design double blind RCT to test the hypothesis that oral vitamin D3...

BACKGROUND Vitamin D deficiency has been associated with cardiovascular risk factors, including type 2 diabetes mellitus (T2DM). Evidence shows that patients with low serum 25-hydroxyvitamin D (25OHD) concentrations have a higher risk of developing coronary artery disease. OBJECTIVE The objective of this study was to assess vitamin D as a predictor of the severity in diabetics with acute coro...

Abstract Background Many international medical organizations recommend vitamin D supplementation for infants, especially exclusively breastfed infants. In Thailand, however, data regarding the status in Thai infants are lacking. Such would help to support physician decisions and guide practice. Methods Full-term, were randomized into two groups at 2 months of age continue exclusive breastfeedin...

Values of serum 25-hydroxyvitamin D (25OHD) defined as insufficient or deficient are common in the general community, particularly among the elderly and people with chronic illnesses and reduced skin exposure to sunlight. Ultraviolet B exposure is essential for skin synthesis of vitamin D3 (cholecalciferol), the precursor to 25OHD3 and 1,25-dihydroxyvitaminD (calcitriol). Dietary sources of vit...

Vitamin D deficiency, which is usually detected by using immunoassays or the more reliable liquid chromatography tandem mass spectrometry (LC-MS/MS) methods, has recently been considered a public health problem worldwide. However, the vitamin D status in Chinese populations, as measured using the LC-MS/MS method, is not available. The objective of this multicenter study was to determine the vit...

<b><i>Introduction:</i></b> Parathyroid hormone-lowering responses after administration of three different therapies capable raising serum total 25-hydroxyvitamin D (25OHD) were evaluated in patients with secondary hyperparathyroidism (SHPT), vitamin insufficiency (VDI), and stage 3 or 4 chronic kidney disease (CKD). <b><i>Methods:</i></b> Sixty-n...

background hypovitaminosis d has been associated with the development of gestational diabetes mellitus (gdm) in many observational studies. objectives we report the first study of the impact of prenatal vitamin d supplementation on postpartum dysglycemia in gdm patients in a randomized clinical trial. patients and methods women with gdm at 12 - 32 weeks of gestation were assigned randomly to ei...

Vitamin D intoxication (VDI) may result from supplementation rarely, but it has been reported more frequently in recent years. This may be attributable to an increase in vitamin D supplement intake due to an understanding of the role of vitamin D (25OHD) in the pathogenesis of several diseases. The symptoms and findings associated with VDI are closely related to serum calcium concentration and ...

Context In older women, the magnitude of elevated parathyroid hormone (PTH) and its consequence is unclear. Objective To describe normal PTH profiles over time and the association with mortality. Design and Participants There were 1044 community-dwelling women in the Malmö Osteoporosis Prospective Risk Assessment cohort (OPRA) who attended baseline (age 75 years). Follow-ups were attended b...