IL-23 is a heterodimeric cytokine composed of the IL-12p40 "soluble receptor" subunit and a novel cytokine-like subunit related to IL-12p35, termed p19. Human and mouse IL-23 exhibit some activities similar to IL-12, but differ in their capacities to stimulate particular populations of memory T cells. Like IL-12, IL-23 binds to the IL-12R subunit IL-12Rbeta1. However, it does not use IL-12Rbeta...

introduction: elective upper and lower gi endoscopy is usually performed in children on an outpatient basis with the child under sedation or general anesthesia (ga). the objective of this study was to describe anesthesia related complications in   children undergoing elective gi endoscopy.   materials and methods: the study design was descriptive on 1388 patients undergoing elective gi endoscop...

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). In MS, myeloid dendritic cells (mDCs) secrete elevated amounts of IL-23, a potent proinflammatory cytokine, compared to healthy donors. Here, we examined the role of CD46, a complement binding factor, in mDCs by analyzing cytokine and chemokine production in healthy donors and patients with MS. There ...

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A lower time bound Ω(min(ν(x), n − ν(x)) for counting the number of ones in a binary input word x of length n corresponding to the word length of a processor architecture is presented, where ν(x) is the number of ones. The operations available are increment, decrement, bit-wise logical operations, and assignment. The only constant available is zero. An almost matching upper bound is also obtained.

The problem of classifying all tile-k-transitive tilings of the innnite 2-dimensional ribbon (and pinched-ribbon) is shown to be solvable by classifying certain tile-k-transitive tilings of the sphere, for all k 2 N. Complete results are listed for k 3.